(Q43510196)

24 November 2017

Divergent roles of SHP-2 in ERK activation by leptin receptors (English)

1 reference

24 November 2017

9

Flier JS

1 reference

24 November 2017

Bjørbaek C

1

1 reference

24 November 2017

Buchholz RM

2

1 reference

24 November 2017

Davis SM

3

1 reference

24 November 2017

Bates SH

4

1 reference

24 November 2017

Pierroz DD

5

1 reference

24 November 2017

Gu H

6

1 reference

24 November 2017

Neel BG

7

1 reference

24 November 2017

Myers MG Jr

8

1 reference

24 November 2017

language of work or name

English

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publication date

20 November 2000

1 reference

Journal of Biological Chemistry

24 November 2017

1 reference

24 November 2017

276

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24 November 2017

4747-4755

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24 November 2017

7

1 reference

Positional cloning of the mouse obese gene and its human homologue

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Role of leptin in the neuroendocrine response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The role of neuropeptide Y in the antiobesity action of the obese gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Hypothalamic CART is a new anorectic peptide regulated by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Defective STAT signaling by the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Divergent signaling capacities of the long and short isoforms of the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Cytokine receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Activation of downstream signals by the long form of the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin receptor action in hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Protein tyrosine phosphatases in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

The role of SOCS-3 in leptin signaling and leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Pituitary corticotroph SOCS-3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007439200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007439200

1 reference

24 November 2017

1 reference