(Q43553429)

24 November 2017

title

Enhanced ribonucleotide incorporation by an O-helix mutant of Thermus aquaticus DNA polymerase I. (English)

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24 November 2017

Thermus aquaticus

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Ogawa M

1

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24 November 2017

Tosaka A

2

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24 November 2017

Ito Y

3

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24 November 2017

Yoshida S

4

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24 November 2017

Suzuki M

5

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24 November 2017

language of work or name

English

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publication date

1 April 2001

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24 November 2017

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24 November 2017

volume

485

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24 November 2017

issue

3

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24 November 2017

page(s)

197-207

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Function and structure relationships in DNA polymerases

24 November 2017

cites work

1 reference

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7 January 2021

Polymerase structures and function: variations on a theme?

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7 January 2021

Structural and mechanistic relationships between nucleic acid polymerases

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7 January 2021

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution

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7 January 2021

Polymerase structures and mechanism.

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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7 January 2021

Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate

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7 January 2021

Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).

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7 January 2021

A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides

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7 January 2021

Significance of the O-helix residues of Escherichia coli DNA polymerase I in DNA synthesis: dynamics of the dNTP binding pocket

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7 January 2021

Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity

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7 January 2021

Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure

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7 January 2021

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

1 reference

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7 January 2021

Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates

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7 January 2021

A mutant T7 RNA polymerase as a DNA polymerase.

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7 January 2021

A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

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7 January 2021

An attempt to unify the structure of polymerases

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7 January 2021

Choosing the right sugar: how polymerases select a nucleotide substrate

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7 January 2021

Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection

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7 January 2021

Multiple amino acid substitutions allow DNA polymerases to synthesize RNA.

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7 January 2021

Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.

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Incorporation of the guanosine triphosphate analogs 8-oxo-dGTP and 8-NH2-dGTP by reverse transcriptases and mammalian DNA polymerases

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7 January 2021

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

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7 January 2021

Slow rate of phosphodiester bond formation accounts for the strong bias that Taq DNA polymerase shows against 2',3'-dideoxynucleotide terminators

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7 January 2021

How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides

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7 January 2021

Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant

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7 January 2021

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

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7 January 2021

Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix

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7 January 2021

The Protein Data Bank. A computer-based archival file for macromolecular structures

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7 January 2021

10.1016/S0921-8777(00)00081-1

Identifiers

DOI

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24 November 2017

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