(Q43556693)

English

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

24 November 2017

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits (English)

1 reference

Europe PubMed Central

24 November 2017

Alzheimer's disease

0 references

0 references

Cyril C. Curtain

1

1 reference

Europe PubMed Central

24 November 2017

9

1 reference

Europe PubMed Central

24 November 2017

author name string

Ali F

2

1 reference

Europe PubMed Central

24 November 2017

Volitakis I

3

1 reference

Europe PubMed Central

24 November 2017

Cherny RA

4

1 reference

Europe PubMed Central

24 November 2017

Norton RS

5

1 reference

Europe PubMed Central

24 November 2017

Beyreuther K

6

1 reference

Europe PubMed Central

24 November 2017

Barrow CJ

7

1 reference

Europe PubMed Central

24 November 2017

Masters CL

8

1 reference

Europe PubMed Central

24 November 2017

Barnham KJ

10

1 reference

Europe PubMed Central

24 November 2017

language of work or name

0 references

publication date

27 March 2001

1 reference

Europe PubMed Central

24 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

24 November 2017

276

1 reference

Europe PubMed Central

24 November 2017

23

1 reference

Europe PubMed Central

24 November 2017

20466-20473

1 reference

Europe PubMed Central

24 November 2017

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Oxidative stress hypothesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Vesicles of variable sizes produced by a rapid extrusion procedure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Helical structure and self-association in a 13 residue neuropeptide Y Y2 receptor agonist: relationship to biological activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Analysis of zinc binding sites in protein crystal structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Solution structures of micelle-bound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Structural implications derived from the analysis of electron paramagnetic resonance spectra of natural and artificial copper proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

EPR Studies of the Motional Characteristics of the Phospholipid in Functional Reconstituted Sarcoplasmic Reticulum Membrane Vesicles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

17 The spin-labeling technique

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

The amino-terminal peptide of HIV-1 glycoprotein 41 interacts with human erythrocyte membranes: peptide conformation, orientation and aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Commentary and perspective on studies of beta amyloid neurotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Effects of beta-amyloid peptides on the fluidity of membranes from frontal and parietal lobes of human brain. High potencies of A beta 1-42 and A beta 1-43.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Reversible random coil-beta-sheet transition of the Alzheimer beta-amyloid fragment (25-35).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Influence of lipoproteins on microglial degradation of Alzheimer's amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100175200

21 January 2018

Identifiers

10.1074/JBC.M100175200

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43556693&oldid=2100756496"