(Q43578585)

24 November 2017

title

Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation (English)

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24 November 2017

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3

Bernd Bukau

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24 November 2017

2

Axel Mogk

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24 November 2017

1

Peter Tessarz

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24 November 2017

language of work or name

English

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publication date

28 February 2008

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24 November 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

Molecular Microbiology

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24 November 2017

volume

68

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24 November 2017

issue

1

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24 November 2017

page(s)

87-97

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Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

24 November 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Analysis of prion factors in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Multifunctional yeast high-copy-number shuttle vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI(+)] of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Modulation of prion-dependent polyglutamine aggregation and toxicity by chaperone proteins in the yeast model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

M domains couple the ClpB threading motor with the DnaK chaperone activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Hsp104 binds to yeast Sup35 prion fiber but needs other factor(s) to sever it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Amino acid residue 184 of yeast Hsp104 chaperone is critical for prion-curing by guanidine, prion propagation, and thermotolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

AAA+ superfamily ATPases: common structure--diverse function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Chaperone network in the yeast cytosol: Hsp110 is revealed as an Hsp70 nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

HSP104 required for induced thermotolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Dominant gain-of-function mutations in Hsp104p reveal crucial roles for the middle region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Substrate recognition by the AAA+ chaperone ClpB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Role of the processing pore of the ClpX AAA+ ATPase in the recognition and engagement of specific protein substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Successive and synergistic action of the Hsp70 and Hsp100 chaperones in protein disaggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

Hsp70 chaperone machine remodels protein aggregates at the initial step of Hsp70-Hsp100-dependent disaggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2008.06135.X

10.1111/J.1365-2958.2008.06135.X

21 January 2018

Identifiers

DOI

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24 November 2017

1 reference