(Q43581716)

English

Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.

scientific article published in May 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Christian Fuhrer

4

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Europe PubMed Central

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6 November 2019

author name string

C L Smith

1

1 reference

Europe PubMed Central

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6 November 2019

P Mittaud

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

E D Prescott

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S J Burden

5

1 reference

Europe PubMed Central

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6 November 2019

language of work or name

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publication date

1 May 2001

1 reference

Europe PubMed Central

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6 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

21

1 reference

Europe PubMed Central

PMC publication ID

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6 November 2019

9

1 reference

Europe PubMed Central

PMC publication ID

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6 November 2019

3151-3160

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Src interacts with dynamin and synapsin in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family tyrosine kinases and growth factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction of Src family kinases with the acetylcholine receptor in C2 myotubes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the Src family tyrosine kinase Fyn with TrkB

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinase-independent function of Lck in potentiating antigen-specific T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 87K postsynaptic membrane protein from Torpedo is a protein-tyrosine kinase substrate homologous to dystrophin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin and alpha-dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin-induced acetylcholine receptor clustering: an alternative pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic integrins in developing, adult, and mutant muscle: selective association of alpha1, alpha7A, and alpha7B integrins with the neuromuscular junction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family kinases are required for integrin but not PDGFR signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA channel regulation by channel-associated protein tyrosine kinase Src.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for selective inhibition of Src family kinases by PP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An acetylcholine receptor alpha-subunit promoter conferring preferential synaptic expression in muscle of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuregulin-mediated acetylcholine receptor synthesis by protein tyrosine phosphatase SHP2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through focal adhesion kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the vertebrate neuromuscular junction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myogenic cell lines derived from transgenic mice carrying a thermolabile T antigen: a model system for the derivation of tissue-specific and mutation-specific cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARIA: a neuromuscular junction neuregulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuregulin-increased expression of acetylcholine receptor epsilon-subunit gene requires ErbB interaction with Shc.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential roles of agrin, MuSK and rapsyn during neuromuscular junction formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-related molecules are concentrated at acetylcholine receptor clusters in normal and aneural developing muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural domains of agrin required for clustering of nicotinic acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-bound agrin induces expression of acetylcholine receptor epsilon-subunit gene in cultured mammalian muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The agrin hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentration of acetylcholine receptor mRNA in synaptic regions of adult muscle fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular calcium regulates agrin-induced acetylcholine receptor clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional role for specific spliced variants of the alpha7beta1 integrin in acetylcholine receptor clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The formation of neuromuscular synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial restriction of AChR gene expression to subsynaptic nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuregulins in development

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of acetylcholine receptor gene expression by ARIA requires activation of mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuregulins and their receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of alpha-dystrobrevin in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of the binding of synapsin I to Src homology 3 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin induces phosphorylation of the nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin can mediate acetylcholine receptor gene expression in muscle by aggregation of muscle-derived neuregulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/11312300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-09-03151.2001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11312300%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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