(Q43588003)

English

Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus

scientific article published on November 1, 2003

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scholarly article

1 reference

Europe PubMed Central

24 November 2017

Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus (English)

1 reference

Europe PubMed Central

24 November 2017

secondary metabolite

1 reference

based on heuristic

inferred from title

horizontal gene transfer

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595556

27 March 2024

catalytic domain

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595556

27 March 2024

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

1

1 reference

Europe PubMed Central

24 November 2017

language of work or name

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14595556

27 March 2024

publication date

1 November 2003

1 reference

Europe PubMed Central

24 November 2017

full work available at URL

http://link.springer.com/content/pdf/10.1007/s00438-003-0937-9.pdf

Portable Document Format

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

http://link.springer.com/article/10.1007/s00438-003-0937-9/fulltext.html

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

http://link.springer.com/content/pdf/10.1007/s00438-003-0937-9

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

Molecular Genetics and Genomics

1 reference

Europe PubMed Central

24 November 2017

270

1 reference

Europe PubMed Central

24 November 2017

420-431

1 reference

Europe PubMed Central

24 November 2017

5

1 reference

Europe PubMed Central

24 November 2017

https://scigraph.springernature.com/pub.10.1007/s00438-003-0937-9

0 references

Polyketide synthase genes from marine dinoflagellates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lateral gene transfer and the nature of bacterial innovation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular archaeology of the Escherichia coli genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selfish operons: horizontal transfer may drive the evolution of gene clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multifunctional polyketide-peptide synthetase essential for albicidin biosynthesis in Xanthomonas albilineans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the evolution of functional secondary metabolites (natural products)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial biosynthesis of 'unnatural' natural products: the polyketide example

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Codon bias and base composition are poor indicators of horizontally transferred genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for detecting positive selection at single amino acid sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel exchangeable effector loci associated with the Pseudomonas syringae hrp pathogenicity island: evidence for integron-like assembly from transposed gene cassettes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid substitution matrices from protein blocks

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple hybrid polyketide synthase/non-ribosomal peptide synthetase gene clusters in the myxobacterium Stigmatella aurantiaca

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transposable elements and adaptation of host bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyketide biosynthesis: a millennium review

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer is a major factor in bacterial evolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: an hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance and specificity of polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for transfer of antibiotic-resistance genes in soil populations of streptomycetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple peptide synthetase gene clusters in Actinomycetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three R's of bacterial evolution: how replication, repair, and recombination frame the origin of species

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppression by discodermolide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene amplification and genomic plasticity in prokaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and heterologous expression of the epothilone gene cluster.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Horizontal gene transfer in microbial genome evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Contributions to Understanding Polyketide Synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pfam protein families database

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Horizontal gene transfer in prokaryotes: quantification and classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic diversity in myxobacteria: identification of the myxalamid and the stigmatellin biosynthetic gene cluster of Stigmatella aurantiaca Sg a15 and a combined polyketide-(poly)peptide gene cluster from the epothilone producing strain Sorangium

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Directional mutation pressure, selective constraints, and genetic equilibria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Horizontal gene transfer among microbial genomes: new insights from complete genome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14595556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GCUA: general codon usage analysis

31

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

Selection and gene duplication: a view from the genome

54

1 reference

10.1007/S00438-003-0937-9

https://api.crossref.org/works/10.1007/S00438-003-0937-9

27 March 2024

Identifiers

10.1007/S00438-003-0937-9

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

ResearchGate publication ID

0 references

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