(Q43620555)

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Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones

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scholarly article

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Europe PubMed Central

25 November 2017

Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones (English)

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Europe PubMed Central

25 November 2017

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Christopher J. Moody

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Europe PubMed Central

25 November 2017

author name string

Winski SL

1

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Europe PubMed Central

25 November 2017

Swann E

2

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Europe PubMed Central

25 November 2017

Hargreaves RH

3

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Europe PubMed Central

25 November 2017

Dehn DL

4

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Europe PubMed Central

25 November 2017

Butler J

5

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Europe PubMed Central

25 November 2017

Ross D

7

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25 November 2017

language of work or name

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publication date

1 June 2001

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25 November 2017

Biochemical Pharmacology

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25 November 2017

61

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25 November 2017

1509-1516

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25 November 2017

12

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25 November 2017

describes a project that uses

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Mitomycin C: a review

1 reference

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The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity

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Metabolic activation of mitomycin C by liver microsomes and nuclei

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Bioreductive activation of mitomycin C by DT-diaphorase

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Re-evaluation of the molecular pharmacology of mitomycin C.

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Cytosolic NAD(P)H:(quinone-acceptor)oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol

1 reference

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7 January 2021

High levels of expression of the NAD(P)H:Quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin

1 reference

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7 January 2021

Immunological quantitation of DT-diaphorase in carcinoma cell lines and clinical colon cancers: advanced tumors express greater levels of DT-diaphorase.

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DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?

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Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9.

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7 January 2021

Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).

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7 January 2021

Indolequinone Antitumor Agents: Correlation between Quinone Structure, Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase, and in Vitro Cytotoxicity1

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2-Cyclopropylindoloquinones and their analogues as bioreductively activated antitumor agents: structure-activity in vitro and efficacy in vivo

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Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Comet assay studies on the activation of two diaziridinylbenzoquinones in K562 cells

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7 January 2021

Indolequinone antitumor agents: Relationship between quinone structure and rate of metabolism by recombinant human NQO1

1 reference

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7 January 2021

DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C.

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7 January 2021

The enzymology of doxorubicin quinone reduction in tumour tissue

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DT-diaphorase-catalysed reduction of 1,4-naphthoquinone derivatives and glutathionyl-quinone conjugates. Effect of substituents on autoxidation rates

1 reference

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7 January 2021

Potential central nervous system antitumor agents. Aziridinylbenzoquinones.

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7 January 2021

Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis

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7 January 2021

Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells

1 reference

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7 January 2021

The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells

1 reference

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7 January 2021

Quinone-induced apoptosis in human colon adenocarcinoma cells via DT-diaphorase mediated bioactivation

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7 January 2021

Identifiers

10.1016/S0006-2952(01)00631-1

1 reference

Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

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