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Predicting drug-resistant mutations of HIV protease

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Europe PubMed Central

25 November 2017

Predicting drug-resistant mutations of HIV protease (English)

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25 November 2017

1

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25 November 2017

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Arieh Warshel

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PubMed ID

18058968

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25 November 2017

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English

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1 January 2008

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Angewandte Chemie International Edition

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47

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4

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25 November 2017

697-700

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25 November 2017

DMP 323, a nonpeptide cyclic urea inhibitor of human immunodeficiency virus (HIV) protease, specifically and persistently blocks intracellular processing of HIV gag polyprotein

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https://api.crossref.org/works/10.1002%2FANIE.200704178

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21 January 2018

Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities

1 reference

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Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors

1 reference

11 October 2022

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Active human immunodeficiency virus protease is required for viral infectivity

1 reference

11 October 2022

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Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas

1 reference

11 October 2022

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Catalysis and linear free energy relationships in aspartic proteases.

1 reference

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Electrostatic contributions to protein-protein binding affinities: application to Rap/Raf interaction

1 reference

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Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.

1 reference

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Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution

1 reference

11 October 2022

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Computational prediction of structure, substrate binding mode, mechanism, and rate for a malaria protease with a novel type of active site

1 reference

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Structure and mechanism of the pepsin-like family of aspartic peptidases

1 reference

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Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure

1 reference

11 October 2022

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DOI

10.1002/ANIE.200704178

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stated in

Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

PubMed ID

18058968

retrieved

25 November 2017

(Q43626086)

Predicting drug-resistant mutations of HIV protease

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