(Q43633322)

25 November 2017

title

First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice (English)

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25 November 2017

J G Filser

1

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25 November 2017

T H Faller

2

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25 November 2017

S Bhowmik

3

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25 November 2017

A Schuster

4

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25 November 2017

W Kessler

5

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25 November 2017

C Pütz

6

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25 November 2017

G A Csanády

7

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25 November 2017

publication date

1 June 2001

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Chemico-biological Interactions

25 November 2017

published in

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25 November 2017

volume

135-136

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25 November 2017

page(s)

249-265

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Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats

25 November 2017

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Gender differences in the metabolism of 1, 3-butadiene in Sprague-Dawley rats following a low level inhalation exposure

7 January 2021

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Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene

7 January 2021

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High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene

7 January 2021

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Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.

7 January 2021

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Comparison of the disposition of butadiene epoxides in Sprague-Dawley rats and B6C3F1 mice following a single and repeated exposures to 1,3-butadiene via inhalation

7 January 2021

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Analysis of butadiene, butadiene monoxide, and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy

7 January 2021

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Mechanisms of 1,3-butadiene oxidations to butadiene monoxide and crotonaldehyde by mouse liver microsomes and chloroperoxidase

7 January 2021

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Inhalation pharmacokinetics based on gas uptake studies. VI. Comparative evaluation of ethylene oxide and butadiene monoxide as exhaled reactive metabolites of ethylene and 1,3-butadiene in rats

7 January 2021

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Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

7 January 2021

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The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein

7 January 2021

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Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice

7 January 2021

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Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man

7 January 2021

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Concentration-dependent depletion of non-protein sulfhydryl (NPSH) content in lung, heart and liver tissue of rats and mice after acute inhalation exposure to butadiene

7 January 2021

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Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice

7 January 2021

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A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.

7 January 2021

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Metabolism of 1,3-butadiene: inhalation pharmacokinetics and tissue dosimetry of butadiene epoxides in rats and mice

7 January 2021

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Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2- epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats

7 January 2021

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PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism

7 January 2021

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A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts--relevance of glutathione depletion.

7 January 2021

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Characterization of urinary metabolites from Sprague-Dawley rats and B6C3F1 mice exposed to [1,2,3,4-13C]butadiene

7 January 2021

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Gas chromatographic determination of 3-butene-1,2-diol in urine samples after 1,3-butadiene exposure

7 January 2021

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Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes

7 January 2021

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Adenine adducts with diepoxybutane: isolation and analysis in exposed calf thymus DNA.

7 January 2021

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7 January 2021

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The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro.

7 January 2021

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Species differences in urinary butadiene metabolites: comparisons of metabolite ratios between mice, rats, and humans

7 January 2021

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The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

7 January 2021

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The effect of some carbonyl compounds on rat liver glutathione levels

7 January 2021

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Inhalation pharmacokinetics based on gas uptake studies. V. Comparative pharmacokinetics of ethylene and 1,3-butadiene in rats

7 January 2021

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Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics

7 January 2021

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Mutagenicity and chemical reactivity of epoxidic intermediates of the isoprene metabolism and other structurally related compounds.

7 January 2021

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Oxidation of 3-butene-1,2-diol by alcohol dehydrogenase.

7 January 2021

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A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man.

7 January 2021

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Quantitative and qualitative differences in the metabolism of 14C-1,3-butadiene in rats and mice: relevance to cancer susceptibility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900194-6

10.1016/S0009-2797(01)00194-6

7 January 2021

Identifiers

DOI

1 reference

25 November 2017

1 reference