(Q43639295)

25 November 2017

A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells (English)

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25 November 2017

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4

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25 November 2017

J Gao

1

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25 November 2017

O Murase

series ordinal

2

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25 November 2017

R L Schowen

series ordinal

3

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25 November 2017

R T Borchardt

series ordinal

5

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25 November 2017

language of work or name

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1 February 2001

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25 November 2017

Pharmaceutical Research

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25 November 2017

18

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25 November 2017

171-176

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25 November 2017

2

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Taxol transport by human intestinal epithelial Caco-2 cells.

25 November 2017

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12 December 2020

Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells

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12 December 2020

Radioligand-binding assay employing P-glycoprotein-overexpressing cells: testing drug affinities to the secretory intestinal multidrug transporter.

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12 December 2020

Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells.

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12 December 2020

Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump

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12 December 2020

Use of membrane vesicles to investigate drug interactions with transporter proteins, P-glycoprotein and multidrug resistance-associated protein

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12 December 2020

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

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12 December 2020

Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay.

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12 December 2020

Interaction of bioactive hydrophobic peptides with the human multidrug transporter

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12 December 2020

Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities

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12 December 2020

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

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12 December 2020

Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells

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12 December 2020

P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil

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12 December 2020

Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells

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12 December 2020

Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

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12 December 2020

Taxol: mechanisms of action and resistance.

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12 December 2020

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

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12 December 2020

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

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12 December 2020

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

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12 December 2020

Metabolism, uptake, and transepithelial transport of the stereoisomers of Val-Val-Val in the human intestinal cell line, Caco-2.

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12 December 2020

Role of P-glycoprotein in drug disposition

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12 December 2020

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

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12 December 2020

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

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12 December 2020

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

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12 December 2020

Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor.

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12 December 2020

Identifiers

DOI

10.1023/A:1011076217118

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25 November 2017

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