(Q43640204)

25 November 2017

title

Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron (English)

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25 November 2017

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1

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25 November 2017

C Mouralian

2

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25 November 2017

P Ponka

series ordinal

3

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25 November 2017

E Becker

series ordinal

4

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25 November 2017

publication date

1 May 2001

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Biochimica et Biophysica Acta

25 November 2017

published in

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25 November 2017

volume

1536

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25 November 2017

issue

2-3

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25 November 2017

page(s)

133-140

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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

25 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria

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7 January 2021

Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue

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7 January 2021

The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle

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https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia

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7 January 2021

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

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7 January 2021

Pathology of the Heart in Friedreich's Ataxia: Review of the Literature and Report of One Case

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7 January 2021

Erythrocyte Protoporphyrin Levels in Patients with Friedreich's and other Ataxias

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7 January 2021

Mobilization of iron from reticulocytes. Identification of pyridoxal isonicotinoyl hydrazone as a new iron chelating agent

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7 January 2021

The effect of various chelating agents on the mobilization of iron from reticulocytes in the presence and absence of pyridoxal isonicotinoyl hydrazone

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7 January 2021

A study of intracellular iron metabolism using pyridoxal isonicotinoyl hydrazone and other synthetic chelating agents

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7 January 2021

Effective Iron Chelation following Oral Administration of an Isoniazid-Pyridoxal Hydrazone

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7 January 2021

Biliary iron excretion in rats following pyridoxal isonicotinoyl hydrazone

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7 January 2021

Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease

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7 January 2021

Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs

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7 January 2021

The biologically active iron chelators 2-pyridylcarboxaldehyde isonicotinoylhydrazone, 2-pyridylcarboxaldehyde benzoylhydrazone monohydrate and 2-furaldehyde isonicotinoylhydrazone

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7 January 2021

Succinylacetone, a potent inhibitor of heme biosynthesis: Effect on cell growth, heme content and δ-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells

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7 January 2021

Iron utilization in rabbit reticulocytes. A study using succinylacetone as an inhibitor or heme synthesis

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7 January 2021

The effects of inhibition of heme synthesis on the intracellular localization of iron in rat reticulocytes

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7 January 2021

Chelator-mediated iron efflux from reticulocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Effect of pyridoxal isonicotinoyl hydrazone and other hydrazones on iron release from macrophages, reticulocytes and hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

A study of the mechanism of action of pyridoxal isonicotinoyl hydrazone at the cellular level using reticulocytes loaded with non-heme 59Fe

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900041-2

7 January 2021

10.1016/S0925-4439(01)00041-2

Identifiers

DOI

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25 November 2017

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