(Q43641485)

English

Synthesis, cytotoxicity, DNA interaction and topoisomerase II inhibition properties of tetrahydropyrrolo[3,4-a]carbazole-1,3-dione and tetrahydropyrido-[3,2-b]pyrrolo[3,4-g]indole-1,3-dione derivatives.

scientific article published in June 2001

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scholarly article

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8 November 2019

Synthesis, cytotoxicity, DNA interaction and topoisomerase II inhibition properties of tetrahydropyrrolo[3,4-a]carbazole-1,3-dione and tetrahydropyrido-[3,2-b]pyrrolo[3,4-g]indole-1,3-dione derivatives (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408172%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1

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8 November 2019

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M Facompré

2

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8 November 2019

H Da Costa

3

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8 November 2019

S Routier

4

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8 November 2019

J Y Mérour

5

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8 November 2019

P Colson

6

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8 November 2019

C Houssier

7

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8 November 2019

C Bailly

8

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8 November 2019

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1 June 2001

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8 November 2019

Bioorganic & Medicinal Chemistry

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8 November 2019

9

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8 November 2019

6

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8 November 2019

1533-1541

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8 November 2019

DNA and associated targets for drug design

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From amsacrine to DACA (N-[2-(dimethylamino)ethyl]acridine-4-carboxamide): selectivity for topoisomerases I and II among acridine derivatives

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Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide

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DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.

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DNA topoisomerases as targets for the anticancer drug TAS-103: primary cellular target and DNA cleavage enhancement

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DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin

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Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

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Synthesis and evaluation of 9-hydroxy-5-methyl-(and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazole-1-N- [(dialkylamino)alkyl]carboxamides, a new promising series of antitumor olivacine derivatives

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In situvinylindole synthesis. Diels-alder reactions with maleimides to give tetrahydrocarbazoles

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Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors

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Electric linear dichroism as a new tool to study sequence preference in drug binding to DNA.

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Identifiers

10.1016/S0968-0896(01)00026-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408172%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11408172%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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