(Q43647927)

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Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan

scientific article published in June 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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author name string

Tohyama Y

1

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Yamane F

2

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Merid MF

3

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Diksic M

4

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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publication date

1 June 2001

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

European Neuropsychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

193-202

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Regional distribution of extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the brain of freely moving rats

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Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties

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Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain.

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Postsynaptic 5-HT1A receptors mediate 5-hydroxytryptamine release in the amygdala through a feedback to the caudal linear raphe.

1 reference

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The inhibitory effect of 8-OH-DPAT on the firing activity of dorsal raphe serotoninergic neurons in rats is attenuated by lesion of the frontal cortex.

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Imaging epileptogenic tubers in children with tuberous sclerosis complex using alpha-[11C]methyl-L-tryptophan positron emission tomography.

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Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L-tryptophan

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Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children.

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Increased brain serotonin synthesis in migraine

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Alpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism

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Effects of 5-HT1A receptor antagonists on fluoxetine-induced changes in extracellular serotonin concentrations in rat frontal cortex.

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A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model

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Autoradiographic Measurement of the Rate of Serotonin Synthesis in the Rat Brain

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7 January 2021

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The regional rate of serotonin synthesis estimated by the alpha-methyl-tryptophan method in rat brain from a single time point

1 reference

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Is alpha-methyl-L-tryptophan a good tracer for brain serotonin synthesis measurements, and does the lumped constant vary in different structures of the rat brain?

1 reference

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Does labeled alpha-methyl-L-tryptophan image ONLY blood-brain barrier transport of tryptophan?

1 reference

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7 January 2021

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Brain net unidirectional uptake of alpha-[14c]methyl-L-tryptophan (alpha-MTrp) and its correlation with regional serotonin synthesis, tryptophan incorporation into proteins, and permeability surface area products of tryptophan and alpha-MTrp.

1 reference

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7 January 2021

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Effect of acute and repeated versus sustained administration of the 5-HT1A receptor agonist ipsapirone: electrophysiological studies in the rat hippocampus and dorsal raphe.

1 reference

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7 January 2021

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Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites.

1 reference

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7 January 2021

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inferred from DOI database lookup

WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0924-977X%2801%2900076-1

7 January 2021

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Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1 reference

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7 January 2021

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A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

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Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT

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WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor.

1 reference

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Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis

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Administration of 8-hydroxy-2-(Di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in the rat brain: differences in potency and regional sensitivity

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Characterisation of the binding of [3H]WAY-100635, a novel 5-hydroxytryptamine1A receptor antagonist, to rat brain

1 reference

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Further assessment of the antagonist properties of the novel and selective 5-HT1A receptor ligands (+)-WAY 100 135 and SDZ 216-525

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Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study.

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Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis.

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The acute effects of reserpine and NSD-1015 on the brain serotonin synthesis rate measured by an autoradiographic method

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DL-fenfluramine increases the 5-HT synthesis rate in the terminals while decreasing it in the cell bodies of the rat brain.

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Influence of fluoxetine on regional serotonin synthesis in the rat brain.

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Serotonin synthesis increased in terminals four days after reserpine treatment: an autoradiographic study in rat brain.

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The effect of MDMA (3,4-methylenedioxymethamphetamine) on the 5-HT synthesis rate in the rat brain: an autoradiographic study.

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Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing

1 reference

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7 January 2021

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Synthesis of enantiomerically pure alpha-[14C]methyl-L-tryptophan

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A new method to measure brain serotonin synthesis in vivo. II. A practical autoradiographic method tested in normal and lithium-treated rats

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Effects of acute and chronic administration of the serotonin1A agonist buspirone on serotonin synthesis in the rat brain.

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1 reference

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Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo

1 reference

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The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer

1 reference

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Rapid steady-state analysis of blood-brain transfer of L-Trp in rat, with special reference to the plasma protein binding.

1 reference

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Determination of the lumped constant for the alpha-methyltryptophan method of estimating the rate of serotonin synthesis

1 reference

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Identifiers

10.1016/S0924-977X(01)00076-1

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

release_aoxdud23qza2rdylscs3l4cede

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24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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