(Q43670360)

English

Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes

scientific article published in August 2001

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scholarly article

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Europe PubMed Central

25 November 2017

Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes (English)

1 reference

Europe PubMed Central

25 November 2017

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author name string

Fulgencio JP

1

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Europe PubMed Central

25 November 2017

Kohl C

2

1 reference

Europe PubMed Central

25 November 2017

Girard J

3

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Europe PubMed Central

25 November 2017

Pégorier JP

4

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Europe PubMed Central

25 November 2017

language of work or name

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publication date

1 August 2001

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Europe PubMed Central

25 November 2017

Biochemical Pharmacology

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Europe PubMed Central

25 November 2017

62

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Europe PubMed Central

25 November 2017

4

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Europe PubMed Central

25 November 2017

439-446

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Europe PubMed Central

25 November 2017

The antihyperglycaemic effect of metformin: therapeutic and cellular mechanisms

1 reference

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Biguanides may produce hypoglycemic action in isolated rat hepatocytes through their effects on L-alanine transport

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Effects of metformin on lactate uptake and gluconeogenesis in the perfused rat liver

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Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes.

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A proposal for the locus of metformin's clinical action: potentiation of the activation of pyruvate kinase by fructose-1,6-diphosphate

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Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin

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Metformin and free fatty acid metabolism

1 reference

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Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production

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Effects of troglitazone and metformin on glucose and lipid metabolism: alterations of two distinct molecular pathways

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Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols

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Interactions in vivo between oxidation of non-esterified fatty acids and gluconeogenesis in the newborn rat

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Dominant role of glucagon in the initial induction of phosphoenolpyruvate carboxykinase mRNA in cultured hepatocytes from fetal rats

1 reference

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Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells

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Glucose-6-phosphatase mRNA and activity are increased to the same extent in kidney and liver of diabetic rats.

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Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-CoA synthases are encoded by two different genes

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Probability tables for individual comparisons by ranking methods

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Mechanism by which metformin reduces glucose production in type 2 diabetes

1 reference

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Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats.

1 reference

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7 January 2021

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

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Results of a placebo-controlled study of the metabolic effects of the addition of metformin to sulfonylurea-treated patients. Evidence for a central role of adipose tissue

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Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study

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Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

1 reference

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7 January 2021

Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin.

1 reference

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7 January 2021

Effect of metformin on SGLT1, GLUT2, and GLUT5 hexose transporter gene expression in small intestine from rats

1 reference

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7 January 2021

Troglitazone inhibits expression of the phosphoenolpyruvate carboxykinase gene by an insulin-independent mechanism

1 reference

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7 January 2021

Mechanisms decreasing glucose oxidation in diabetes and starvation: role of lipid fuels and hormones.

1 reference

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7 January 2021

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10.1016/S0006-2952(01)00679-7

1 reference

Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

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