(Q43714919)

English

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex

scientific article published in September 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1 reference

based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

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based on heuristic

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author name string

J B Almond

1

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

R T Snowden

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

A Hunter

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

D Dinsdale

4

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

K Cain

5

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

G M Cohen

6

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

publication date

1 September 2001

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1388-1397

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Chronic lymphocytic leukemia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

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Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondria and apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

The proteasome: paradigm of a self-compartmentalizing protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Programmed cell death and the proteasome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the ubiquitin-proteasome pathway in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis induction resulting from proteasome inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the cell death program by inhibition of proteasome function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent induction of apoptosis by proteasome inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptidyl aldehyde inhibitors of proteasome induce apoptosis rapidly in mouse lymphoma RVC cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteasomes play an essential role in thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Dissociation of phagocyte recognition of cells undergoing apoptosis from other features of the apoptotic program

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

A flow-cytometric method for the separation and quantitation of normal and apoptotic thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased membrane permeability of apoptotic thymocytes: a flow cytometric study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Lactacystin, proteasome function, and cell fate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteasome inhibitors: valuable new tools for cell biologists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondria and programmed cell death: back to the future.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-9 and APAF-1 form an active holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402201

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2402201

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

ResearchGate publication ID

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