(Q43714923)

26 November 2017

Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells (English)

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26 November 2017

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acute myeloid leukemia

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6

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26 November 2017

Xia Z

1

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26 November 2017

Tan MM

2

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26 November 2017

Wong WW

3

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26 November 2017

Dimitroulakos J

4

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26 November 2017

Minden MD

5

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26 November 2017

1 September 2001

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26 November 2017

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26 November 2017

15

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26 November 2017

9

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26 November 2017

1398-1407

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402196

26 November 2017

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cites work

Regulation of the mevalonate pathway

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Bile acid biosynthesis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Relationships among dolichyl phosphate, glycoprotein synthesis, and cell culture growth

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Lovastatin induces apoptosis in malignant mesothelioma cells.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: lovastatin specifically targets P-glycoprotein-expressing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Lovastatin induced control of blast cell growth in an elderly patient with acute myeloblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

HMG-CoA reductase inhibitors induce apoptosis in mouse proximal tubular cells in primary culture

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Cholesterol biosynthesis and metabolism

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Features of apoptotic cells measured by flow cytometry

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Geranylgeranylation of Rab proteins

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Mevalonate prevents lovastatin-induced apoptosis in medulloblastoma cell lines.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Induction of apoptosis in p53-null HL-60 cells by inhibition of lanosterol 14-alpha demethylase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Cholesterol, but not its esters, triggers programmed cell death in human erythroleukemia K562 cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Protein prenylation: molecular mechanisms and functional consequences

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Dual role of Ras and Rho proteins: at the cutting edge of life and death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Farnesyltransferase inhibitors: antineoplastic mechanism and clinical prospects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Specific labeling of isoprenylated proteins: application to study inhibitors of the post-translational farnesylation and geranylgeranylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402196

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402196

1 reference

Dimensions Publication ID

26 November 2017

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