(Q43763036)

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L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system

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scholarly article

1 reference

Europe PubMed Central

26 November 2017

L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system (English)

1 reference

Europe PubMed Central

26 November 2017

author name string

Tomoko Sayano

1

1 reference

Europe PubMed Central

26 November 2017

Yuriko Kawakami

2

1 reference

Europe PubMed Central

26 November 2017

Wataru Kusada

3

1 reference

Europe PubMed Central

26 November 2017

Takeshi Suzuki

4

1 reference

Europe PubMed Central

26 November 2017

Yuki Kawano

5

1 reference

Europe PubMed Central

26 November 2017

Akihiro Watanabe

6

1 reference

Europe PubMed Central

26 November 2017

Kana Takashima

7

1 reference

Europe PubMed Central

26 November 2017

Yashiho Arimoto

8

1 reference

Europe PubMed Central

26 November 2017

Kayoko Esaki

9

1 reference

Europe PubMed Central

26 November 2017

Akira Wada

10

1 reference

Europe PubMed Central

26 November 2017

Fumiaki Yoshizawa

11

1 reference

Europe PubMed Central

26 November 2017

Masahiko Watanabe

12

1 reference

Europe PubMed Central

26 November 2017

Masahiro Okamoto

13

1 reference

Europe PubMed Central

26 November 2017

Yoshio Hirabayashi

14

1 reference

Europe PubMed Central

26 November 2017

Shigeki Furuya

15

1 reference

Europe PubMed Central

26 November 2017

language of work or name

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publication date

24 February 2013

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Europe PubMed Central

26 November 2017

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Europe PubMed Central

26 November 2017

280

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Europe PubMed Central

26 November 2017

6

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26 November 2017

1502-1517

1 reference

Europe PubMed Central

26 November 2017

Molecular characterization of 3-phosphoglycerate dehydrogenase deficiency--a neurometabolic disorder associated with reduced L-serine biosynthesis

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Segmental and complementary expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase and neutral amino acid transporter ASCT1 in the mouse kidney.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Resurgence of serine: an often neglected but indispensable amino Acid

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Serine racemase and the serine shuttle between neurons and astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

L-serine synthesis in the central nervous system: a review on serine deficiency disorders

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Impaired neurogenesis in embryonic spinal cord of Phgdh knockout mice, a serine deficiency disorder model

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Coping with stress: eIF2 kinases and translational control

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

The mRNA 5' cap-binding protein eIF4E and control of cell growth

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Regulation of cap-dependent translation by eIF4E inhibitory proteins

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Asymmetric inheritance of radial glial fibers by cortical neurons

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Translational control of retroviruses.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Notch1 is essential for postimplantation development in mice.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Essential role of endothelial Notch1 in angiogenesis

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Notch signaling in stem cell systems

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Notch signaling in the mammalian central nervous system: insights from mouse mutants

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

A hierarchy of ATP-consuming processes in mammalian cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Activated eIF4E-binding Protein Slows G1 Progression and Blocks Transformation by c-myc without Inhibiting Cell Growth

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Specificity of amino acid regulated gene expression: analysis of genes subjected to either complete or single amino acid deprivation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Signalling to translation: how signal transduction pathways control the protein synthetic machinery

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12146

21 January 2018

Identifiers

10.1111/FEBS.12146

1 reference

Europe PubMed Central

26 November 2017

1 reference

Europe PubMed Central

26 November 2017

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