(Q43771337)

English

Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway.

scientific article published in February 2000

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Europe PubMed Central

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3 November 2019

Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway (English)

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Europe PubMed Central

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3 November 2019

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based on heuristic

inferred from title

Stephen M. Strittmatter

4

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3 November 2019

2

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3 November 2019

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H J Fryer

1

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3 November 2019

R J Knox

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3 November 2019

D Pennica

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3 November 2019

R M O'Leary

6

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3 November 2019

D S Russell

7

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3 November 2019

R G Kalb

8

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3 November 2019

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1 February 2000

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3 November 2019

Journal of Neurochemistry

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3 November 2019

74

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3 November 2019

2

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3 November 2019

582-595

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3 November 2019

Nerve growth factor up-regulates the N-methyl-D-aspartate receptor subunit 1 promoter in PC12 cells.

1 reference

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21 January 2018

The Trk family of neurotrophin receptors

1 reference

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21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

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21 January 2018

Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate sensitivity on glutamate-resistant cerebellar granule cells

1 reference

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21 January 2018

Brain-derived neurotrophic factor and nerve growth factor potentiate excitatory synaptic transmission in the rat visual cortex.

1 reference

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21 January 2018

Neurotrophins live or let die: does p75NTR decide?

1 reference

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21 January 2018

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

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21 January 2018

The p75 neurotrophin receptor

1 reference

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21 January 2018

Grasping objects: the cortical mechanisms of visuomotor transformation

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21 January 2018

Glutamate neurotoxicity and diseases of the nervous system

1 reference

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21 January 2018

The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

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21 January 2018

Regulation of glutaminase activity and glutamine metabolism

1 reference

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21 January 2018

Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways.

1 reference

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21 January 2018

The role of neurotrophins in the developing nervous system

1 reference

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21 January 2018

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

1 reference

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21 January 2018

Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors

1 reference

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21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

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21 January 2018

Lack of excitotoxic cell death in serum-free cultures of rat cerebral cortex.

1 reference

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21 January 2018

Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons

1 reference

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21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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21 January 2018

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

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21 January 2018

An Evaluation of the Role of Calcium in Cell Injury

1 reference

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21 January 2018

Neurotrophic factor therapy for nervous system degenerative diseases

1 reference

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21 January 2018

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

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21 January 2018

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1 reference

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21 January 2018

Neurotrophin signal transduction by the Trk receptor

1 reference

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21 January 2018

A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

1 reference

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21 January 2018

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1 reference

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21 January 2018

Contributory mechanisms in the causation of neurodegenerative disorders

1 reference

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21 January 2018

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors

1 reference

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21 January 2018

Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity

1 reference

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21 January 2018

BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities

1 reference

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21 January 2018

Role of neurotrophins in preventing glutamate induced neuronal cell death

1 reference

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21 January 2018

Trophic protection of motor neurons: clinical potential in motor neuron diseases

1 reference

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21 January 2018

Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

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21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

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21 January 2018

Mechanisms of neurotrophic factor protection against calcium- and free radical-mediated excitotoxic injury: implications for treating neurodegenerative disorders

1 reference

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21 January 2018

Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

1 reference

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21 January 2018

Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus

1 reference

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21 January 2018

The neurotrophic theory and naturally occurring motoneuron death

1 reference

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Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice.

1 reference

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21 January 2018

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons.

1 reference

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Induction of apoptosis by the low-affinity NGF receptor

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The orientation of phosphate activated glutaminase in the inner mitochondrial membrane of synaptic and non-synaptic rat brain mitochondria.

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21 January 2018

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

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Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective.

1 reference

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21 January 2018

Excitotoxicity and motor neurone disease: a review of the evidence

1 reference

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21 January 2018

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1 reference

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21 January 2018

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

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21 January 2018

Characterization of a multicomponent receptor for GDNF.

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21 January 2018

Functional receptor for GDNF encoded by the c-ret proto-oncogene

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Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

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The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons

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21 January 2018

Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

1 reference

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21 January 2018

Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

1 reference

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21 January 2018

Induction of cell death by endogenous nerve growth factor through its p75 receptor

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21 January 2018

Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro

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21 January 2018

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

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21 January 2018

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