(Q43810167)

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T cell receptor-mediated signal transduction controlled by the beta chain transmembrane domain: apoptosis-deficient cells display unbalanced mitogen-activated protein kinases activities upon T cell receptor engagement.

scientific article published on 27 November 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

T cell receptor-mediated signal transduction controlled by the beta chain transmembrane domain: apoptosis-deficient cells display unbalanced mitogen-activated protein kinases activities upon T cell receptor engagement (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

transmembrane protein

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Patricia Fuentes

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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Emma Teixeiro

1

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4 December 2019

Begona Galocha

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Balbino Alarcon

4

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4 December 2019

Rafael Bragado

5

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4 December 2019

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27 November 2001

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4 December 2019

Journal of Biological Chemistry

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4 December 2019

277

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4 December 2019

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4 December 2019

3993-4002

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4 December 2019

The T cell receptor for antigen: signaling and ligand discrimination

1 reference

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21 January 2018

T cell receptor alpha-chain tail is required for protein kinase C-mediated down-regulation, but not for signaling

1 reference

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21 January 2018

A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness.

1 reference

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21 January 2018

Positive selection through a motif in the alphabeta T cell receptor

1 reference

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21 January 2018

A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

1 reference

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21 January 2018

Signaling efficiency of the T cell receptor controlled by a single amino acid in the beta chain constant region

1 reference

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21 January 2018

Transmembrane polar residues of TCR beta chain are required for signal transduction

1 reference

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21 January 2018

Conserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas

1 reference

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21 January 2018

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

1 reference

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21 January 2018

Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide

1 reference

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21 January 2018

Partial activation of foreign antigen specific T lymphocytes by a self peptide: possible roles of altered peptide ligands in regulating T lymphocyte mediated immune response

1 reference

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21 January 2018

Th2 cell clonal anergy as a consequence of partial activation

1 reference

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21 January 2018

Selective induction of apoptosis in mature T lymphocytes by variant T cell receptor ligands.

1 reference

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21 January 2018

Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter

1 reference

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21 January 2018

Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

T cell receptor (TCR) engagement in apoptosis-defective, but interleukin 2 (IL-2)-producing, T cells results in impaired ZAP70/CD3-zeta association.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Apoptosis-resistant T cells have a deficiency in NF-kappaB-mediated induction of Fas ligand transcription.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

New perspectives on PKCtheta, a member of the novel subfamily of protein kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Selective modulation of protein kinase C-theta during T-cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107797200

21 January 2018

A Novel Approach to Antigen-Specific Deletion of CTL with Minimal Cellular Activation Using α3 Domain Mutants of MHC Class I/Peptide Complex

1 reference

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21 January 2018

Differential TCR Signaling Regulates Apoptosis and Immunopathology during Antigen Responses In Vivo

1 reference

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21 January 2018

The Actin Cytoskeleton and Lymphocyte Activation

1 reference

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21 January 2018

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

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21 January 2018

Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

1 reference

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21 January 2018

ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells

1 reference

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21 January 2018

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

1 reference

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21 January 2018

Apoptosis but not other activation events is inhibited by a mutation in the transmembrane domain of T cell receptor beta that impairs CD3zeta association

1 reference

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21 January 2018

Involvement of p21ras activation in T cell CD69 expression

1 reference

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21 January 2018

Raf-1 provides a dominant but not exclusive signal for the induction of CD69 expression on T cells

1 reference

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21 January 2018

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells

1 reference

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21 January 2018

Activation-induced apoptosis of mature T cells is dependent upon the level of surface TCR but not on the presence of the CD3 zeta ITAM

1 reference

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21 January 2018

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

1 reference

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Generation of partial agonist ligands of the T-cell receptor by engineering of antibodies against CD3

1 reference

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CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M107797200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11724779%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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