(Q43815805)

27 November 2017

title

The conserved active site asparagine in class I ribonucleotide reductase is essential for catalysis (English)

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27 November 2017

4

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27 November 2017

3

Margareta Sahlin

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27 November 2017

Alex Kasrayan

1

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27 November 2017

Annika L Persson

series ordinal

2

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27 November 2017

language of work or name

English

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publication date

3 December 2001

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

8

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27 November 2017

page(s)

5749-5755

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Ribonucleotide reductases

27 November 2017

cites work

1 reference

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Thiyl radicals in ribonucleotide reductases.

21 January 2018

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Glycyl radical enzymes: a conservative structural basis for radicals

21 January 2018

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Three-dimensional structure of the free radical protein of ribonucleotide reductase

21 January 2018

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Structure of ribonucleotide reductase protein R1

21 January 2018

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Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding

21 January 2018

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Characterization of C439SR1, a mutant of Escherichia coli ribonucleotide diphosphate reductase: evidence that C439 is a residue essential for nucleotide reduction and C439SR1 is a protein possessing novel thioredoxin-like activity

21 January 2018

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Interaction of C225SR1 mutant subunit of ribonucleotide reductase with R2 and nucleoside diphosphates: tales of a suicidal enzyme

21 January 2018

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Structure and function of the Escherichia coli ribonucleotide reductase protein R2

21 January 2018

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Kinetic evidence that a radical transfer pathway in protein R2 of mouse ribonucleotide reductase is involved in generation of the tyrosyl free radical

21 January 2018

1 reference

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Site-directed mutagenesis and deletion of the carboxyl terminus of Escherichia coli ribonucleotide reductase protein R2. Effects on catalytic activity and subunit interaction.

21 January 2018

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Evidence by site-directed mutagenesis supports long-range electron transfer in mouse ribonucleotide reductase.

21 January 2018

1 reference

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Two conserved tyrosine residues in protein R1 participate in an intermolecular electron transfer in ribonucleotide reductase.

21 January 2018

1 reference

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Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway. The importance of hydrogen bond connections between the participating residues

21 January 2018

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Mechanism of inactivation of Escherichia coli ribonucleotide reductase by 2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a 2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift

21 January 2018

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A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase

21 January 2018

1 reference

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High-field EPR detection of a disulfide radical anion in the reduction of cytidine 5'-diphosphate by the E441Q R1 mutant of Escherichia coli ribonucleotide reductase

21 January 2018

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A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Products of the inactivation of ribonucleoside diphosphate reductase from Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate

21 January 2018

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Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors.

21 January 2018

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Identification of an active site residue of the R1 subunit of ribonucleotide reductase from Escherichia coli: characterization of substrate-induced polypeptide cleavage by C225SR1.

21 January 2018

1 reference

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A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

21 January 2018

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A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing

21 January 2018

1 reference

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Iron ligand mutants in protein R2 of Escherichia coli ribonucleotide reductase

21 January 2018

1 reference

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Evidence by mutagenesis that Tyr(370) of the mouse ribonucleotide reductase R2 protein is the connecting link in the intersubunit radical transfer pathway

21 January 2018

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Ribonucleotide reductases: radical enzymes with suicidal tendencies

21 January 2018

1 reference

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Cysteinyl and Substrate Radical Formation in Active Site Mutant E441Q ofEscherichia coliClass I Ribonucleotide Reductase

21 January 2018

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The ten-stranded beta/alpha barrel in ribonucleotide reductase protein R1

21 January 2018

1 reference

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DISMUTATION REACTIONS OF NUCLEOSIDE POLYPHOSPHATES. II. SPECIFIC CHEMICAL SYNTHESES OF ALPHA-, BETA-, AND GAMMA-P32-NUCLEOSIDE 5'-TRIPHOSPHATES

21 January 2018

1 reference

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Mechanism of inactivation of Escherichia coli and Lactobacillus leichmannii ribonucleotide reductases by 2'-chloro-2'-deoxynucleotides: evidence for generation of 2-methylene-3(2H)-furanone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106538200

21 January 2018

Identifiers

DOI

10.1074/JBC.M106538200

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27 November 2017

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