(Q43816302)

English

PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism

scientific article published in January 2002

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scholarly article

1 reference

Europe PubMed Central

27 November 2017

PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism (English)

1 reference

Europe PubMed Central

27 November 2017

1 reference

based on heuristic

inferred from title

acute myeloid leukemia

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inferred from title

Frederick R. Appelbaum

5

object named as

Frederick R Appelbaum

1 reference

Europe PubMed Central

27 November 2017

Cheryl L. Willman

4

object named as

Cheryl L Willman

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Europe PubMed Central

27 November 2017

author name string

Deborah E Banker

1

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Europe PubMed Central

27 November 2017

John J Cooper

2

1 reference

Europe PubMed Central

27 November 2017

Dean A Fennell

3

1 reference

Europe PubMed Central

27 November 2017

Finbarr E Cotter

6

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Europe PubMed Central

27 November 2017

publication date

1 January 2002

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Europe PubMed Central

27 November 2017

Leukemia Research

1 reference

Europe PubMed Central

27 November 2017

26

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Europe PubMed Central

27 November 2017

91-106

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Europe PubMed Central

27 November 2017

1

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Europe PubMed Central

27 November 2017

The biochemistry of P-glycoprotein-mediated multidrug resistance

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Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma.

1 reference

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7 January 2021

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The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia.

1 reference

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7 January 2021

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High bcl-2 expression in acute myeloid leukemia cells correlates with CD34 positivity and complete remission rate.

1 reference

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7 January 2021

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

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Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia

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A phase I study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide, and the MDR modulator PSC 833: a southwest oncology group study 9617.

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Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells

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Taxol can induce phosphorylation of BCL-2 in multiple myeloma cells and potentiate dexamethasone-induced apoptosis.

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BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

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Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

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The mitochondrial permeability transition.

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7 January 2021

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Caspases: enemies within

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Escaping cell death: survival proteins in cancer

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

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7 January 2021

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Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

1 reference

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7 January 2021

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Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

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7 January 2021

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Investigation of bax-induced release of cytochrome c from yeast mitochondria permeability of mitochondrial membranes, role of VDAC and ATP requirement

1 reference

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7 January 2021

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The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo evaluation in mice and metabolism in blood of human volunteers of [123I]iodo-PK11195: a possible single-photon emission tomography tracer for visualization of inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The Mr 18,000 subunit of the peripheral-type benzodiazepine receptor exhibits both benzodiazepine and isoquinoline carboxamide binding sites in the absence of the voltage-dependent anion channel or of the adenine nucleotide carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Receptors for the Age of Anxiety: Pharmacology of the Benzodiazepines

1 reference

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7 January 2021

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Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands

1 reference

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7 January 2021

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A mammalian mitochondrial drug receptor functions as a bacterial "oxygen" sensor

1 reference

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7 January 2021

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Molecular and functional properties of mitochondrial benzodiazepine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

based on heuristic

inferred from DOI database lookup

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

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inferred from DOI database lookup

Pharmacokinetics and effects on exercise heart rate of PK 11195 (52028 RP), an antagonist of peripheral benzodiazepine receptors, in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2801%2900112-6

7 January 2021

based on heuristic

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Functional antagonism between PK 11195, a peripheral benzodiazepine receptor antagonist, and nicardipine at the vascular level in healthy subjects: a peripheral hemodynamic study

1 reference

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7 January 2021

based on heuristic

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Pilot Study of PK 11195, a Selective Ligand for the Peripheral-Type Benzodiazepine Binding Sites, in Inpatients with Anxious or Depressive Symptomatology

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

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Flow cytometric detection of apoptosis: Comparison of the assays of in situ DNA degradation and chromatin changes

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Comparison of DiOC(6)(3) uptake and annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T lymphocytes from children

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Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

1 reference

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1 reference

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1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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based on heuristic

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Identifiers

10.1016/S0145-2126(01)00112-6

1 reference

Europe PubMed Central

27 November 2017

1 reference

Europe PubMed Central

27 November 2017

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