(Q43869554)

27 November 2017

title

A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets (English)

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27 November 2017

Paolo Lova

1

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27 November 2017

Simona Paganini

2

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27 November 2017

Fabiola Sinigaglia

3

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27 November 2017

Cesare Balduini

4

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27 November 2017

Mauro Torti

5

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27 November 2017

language of work or name

English

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publication date

28 January 2002

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

14

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27 November 2017

page(s)

12009-12015

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Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells

27 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

21 January 2018

1 reference

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Rap1 signalling: adhering to new models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Role of rap1B and p21ras GTPase-activating protein in the regulation of phospholipase C-gamma 1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Sequential regulation of the small GTPase Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

21 January 2018

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Identification of the platelet ADP receptor targeted by antithrombotic drugs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111803200

ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

21 January 2018

1 reference

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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

21 January 2018

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Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

21 January 2018

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A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis.

21 January 2018

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An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function

21 January 2018

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Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP

21 January 2018

1 reference

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Association of the low molecular weight GTP-binding protein rap2B with the cytoskeleton during platelet aggregation

21 January 2018

1 reference

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Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen

21 January 2018

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Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism

21 January 2018

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ADP receptors and clinical bleeding disorders

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111803200

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111803200

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Epinephrine suppresses rap1B.GAP-activated GTPase activity in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Src tyrosine kinase is a novel direct effector of G proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

Epinephrine induces association of pp60src with Gi alpha in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111803200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111803200

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27 November 2017

1 reference