(Q43901688)

English

Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.

scientific article published on 28 February 2002

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scholarly article

1 reference

Europe PubMed Central

27 November 2017

Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6. (English)

1 reference

Europe PubMed Central

27 November 2017

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phosphorylation

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based on heuristic

inferred from title

multiple myeloma

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based on heuristic

inferred from title

author name string

Yijiang Shi

1

1 reference

Europe PubMed Central

27 November 2017

Jung-hsin Hsu

2

1 reference

Europe PubMed Central

27 November 2017

Liping Hu

3

1 reference

Europe PubMed Central

27 November 2017

Joseph Gera

4

1 reference

Europe PubMed Central

27 November 2017

Alan Lichtenstein

5

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Europe PubMed Central

27 November 2017

language of work or name

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publication date

28 February 2002

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Europe PubMed Central

27 November 2017

number of pages

9

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Journal of Biological Chemistry

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Europe PubMed Central

27 November 2017

277

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Europe PubMed Central

27 November 2017

18

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27 November 2017

15712-15720

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Europe PubMed Central

27 November 2017

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Interleukin 6 is essential for in vivo development of B lineage neoplasms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

The AKT kinase is activated in multiple myeloma tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Interleukin 3-dependent survival by the Akt protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

The akt kinase: molecular determinants of oncogenicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Ribosomal S6 kinase signaling and the control of translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200043200

21 January 2018

Identifiers

10.1074/JBC.M200043200

1 reference

Europe PubMed Central

27 November 2017

release_odpdm23w45agzl4r66xrlzfs6m

1 reference

https://api.fatcat.wiki/v0/release/odpdm23w45agzl4r66xrlzfs6m

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

27 November 2017

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