(Q43904711)

English

Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes

scientific article published on 4 March 2002

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Europe PubMed Central

PubMed publication ID

27 November 2017

Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes (English)

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Europe PubMed Central

PubMed publication ID

27 November 2017

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Bang Yeon Hwang

3

object named as

Bang Yeon Hwang

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Europe PubMed Central

PubMed publication ID

27 November 2017

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Jeong-Hyung Lee

1

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Europe PubMed Central

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27 November 2017

Tae Hyeon Koo

2

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27 November 2017

Jung Joon Lee

4

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27 November 2017

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publication date

4 March 2002

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PubMed publication ID

27 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

27 November 2017

277

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Europe PubMed Central

PubMed publication ID

27 November 2017

21

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Europe PubMed Central

PubMed publication ID

27 November 2017

18411-18420

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Europe PubMed Central

PubMed publication ID

27 November 2017

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

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21 January 2018

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1 reference

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21 January 2018

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

1 reference

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21 January 2018

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

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21 January 2018

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

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21 January 2018

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Kaurane diterpenes from Isodon japonicus inhibit nitric oxide and prostaglandin E2 production and NF-kappaB activation in LPS-stimulated macrophage RAW264.7 cells

1 reference

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21 January 2018

Novel application of S-nitrosoglutathione-Sepharose to identify proteins that are potential targets for S-nitrosoglutathione-induced mixed-disulphide formation

1 reference

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21 January 2018

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1 reference

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21 January 2018

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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21 January 2018

Inhibition of NF-kappaB DNA binding by nitric oxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Inhibition of NF-kappa B by S-nitrosylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Structure of the NF-kappa B p50 homodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65

1 reference

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21 January 2018

The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Inhibition of HIV-1 replication and NF-kappa B activity by cysteine and cysteine derivatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Cytotoxic and antitumor activities of Rabdosia diterpenoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Structural elucidation of new diterpenoids isolated from Rabdosia umbrosa var. leucantha f. Kameba

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

The antitumor and antibacterial activity of the Isodon diterpenoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201368200

21 January 2018

Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of action

1 reference

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21 January 2018

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M201368200

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

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