(Q43906981)

PubMed publication ID

11880497

27 November 2017

title

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells (English)

1 reference

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12 May 2020

6

1 reference

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12 May 2020

author name string

Heiko Runz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

Jens Rietdorf

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

Inge Tomic

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

Marina de Bernard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

Tobias Hartmann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

Konrad Beyreuther

5

1 reference

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12 May 2020

language of work or name

English

0 references

publication date

1 March 2002

1 reference

PubMed publication ID

11880497

27 November 2017

published in

Journal of Neuroscience

1 reference

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12 May 2020

volume

22

1 reference

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12 May 2020

issue

5

1 reference

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12 May 2020

page(s)

1679-1689

1 reference

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Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

12 May 2020

cites work

1 reference

12 December 2020

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

1 reference

12 December 2020

Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI

1 reference

12 December 2020

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

1 reference

12 December 2020

Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons

1 reference

12 December 2020

Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.

1 reference

12 December 2020

Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems

1 reference

12 December 2020

Statins and the risk of dementia

1 reference

12 December 2020

Proteolytic processing and cell biological functions of the amyloid precursor protein

1 reference

12 December 2020

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

12 December 2020

Localization of human acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues

1 reference

12 December 2020

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1 reference

12 December 2020

The vacuolar ATPase proton pump is present on intracellular vacuoles induced by Helicobacter pylori.

1 reference

12 December 2020

Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Presenilins and the intramembrane proteolysis of proteins: facts and fiction.

1 reference

12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

12 December 2020

1 reference

12 December 2020

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

1 reference

12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

12 December 2020

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

1 reference

12 December 2020

Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane.

1 reference

12 December 2020

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

1 reference

12 December 2020

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes

1 reference

12 December 2020

Expression of Niemann-Pick type C transcript in rodent cerebellum in vivo and in vitro

1 reference

12 December 2020

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

1 reference

12 December 2020

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

12 December 2020

Generation of beta A4 from the amyloid protein precursor and fragments thereof

1 reference

12 December 2020

Acute cholesterol depletion inhibits clathrin-coated pit budding

1 reference

12 December 2020

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

12 December 2020

Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate

1 reference

12 December 2020

A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance

1 reference

12 December 2020

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

1 reference

12 December 2020

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

1 reference

12 December 2020

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

12 December 2020

Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol

1 reference

12 December 2020

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

1 reference

12 December 2020

Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi

1 reference

12 December 2020

The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein

1 reference

12 December 2020

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

1 reference

12 December 2020

Identification of HE1 as the second gene of Niemann-Pick C disease

1 reference

12 December 2020

The role of cholesterol in the biosynthesis of beta-amyloid

1 reference

12 December 2020

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

1 reference

12 December 2020

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

12 December 2020

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

1 reference

12 December 2020

Increase in membrane cholesterol: a possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells

1 reference

12 December 2020

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

12 December 2020

Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

1 reference

12 December 2020

10.1523/JNEUROSCI.22-05-01679.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758870&resulttype=core&format=json

12 May 2020

PubMed publication ID

11880497

1 reference