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Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation.
scientific article published in January 2002
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
title
Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Eleonora Palma
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Sergio Fucile
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
F Eusebi
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3
1 reference
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Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
R Miledi
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4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
language of work or name
English
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publication date
1 January 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Neuroscience
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
110
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
169-179
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
cites work
Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono- and unliganded receptors
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Crossref
reference URL
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7 January 2021
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Serotonin neurons, neuroplasticity, and homeostasis of neural tissue.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
5-Hydroxytryptamine and atropine inhibit nicotinic receptors in submucosal neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement by 5‐hydroxytryptamine and analogues of desensitization of neuronal and muscle nicotinic receptors expressed in Xenopus oocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The neuronal alpha6 subunit forms functional heteromeric acetylcholine receptors in human transfected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a determinant of acetylcholine receptor gating kinetics in the extracellular portion of the gamma subunit.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human neuronal threonine-for-leucine-248 alpha 7 mutant nicotinic acetylcholine receptors are highly Ca2+ permeable
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of serotonergic agents on neuronal nicotinic acetylcholine receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smoking and Parkinson's disease: a dose-response relationship.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blockage of nicotinic acetylcholine receptors by 5-hydroxytryptamine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of the brain serotonin system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotinic receptors in the brain: correlating physiology with function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smoking and Alzheimer's disease: a review of the epidemiological evidence
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presynaptic nicotinic receptors facilitate monoaminergic transmission.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotinic acetylcholine receptors in health and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presynaptic ionotropic receptors and the control of transmitter release.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presynaptic ionotropic receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A calcium-dependent transient outward current in Xenopus laevis oocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Threonine-for-leucine mutation within domain M2 of the neuronal alpha(7) nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-expression of the neuronal alpha7 and L247T alpha7 mutant subunits yields hybrid nicotinic receptors with properties of both wild-type alpha7 and alpha7 mutant homomeric receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal nicotinic threonine-for-leucine 247 alpha7 mutant receptors show different gating kinetics when activated by acetylcholine or by the noncompetitive agonist 5-hydroxytryptamine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Zn2+ on wild and mutant neuronal alpha7 nicotinic receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strychnine activates neuronal alpha7 nicotinic receptors after mutations in the leucine ring and transmitter binding site domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotinic acetylcholine receptors assembled from the alpha7 and beta3 subunits.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5-HT receptors: past, present and future
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serotonin receptor variants in disease: new therapeutic opportunities?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
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7 January 2021
based on heuristic
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The Hill equation revisited: uses and misuses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2801%2900567-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0306-4522(01)00567-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Fatcat ID
release_hijvc76v2vb5zitmwvigmkes3y
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/hijvc76v2vb5zitmwvigmkes3y
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed publication ID
11882381
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11882381
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11882381%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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