(Q43918933)

28 November 2017

title

Role of antigen receptor affinity in T cell-independent antibody responses in vivo (English)

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28 November 2017

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Michel C. Nussenzweig

series ordinal

3

object named as

Michel C Nussenzweig

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28 November 2017

Tien-An Yang Shih

1

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28 November 2017

Mario Roederer

series ordinal

2

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28 November 2017

language of work or name

English

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publication date

18 March 2002

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28 November 2017

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28 November 2017

volume

3

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28 November 2017

issue

4

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28 November 2017

page(s)

399-406

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T cell-independent antigens type 2.

28 November 2017

cites work

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VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE

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Cell Selection by Antigen in the Immune Response

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The immunological properties of haptens coupled to thymus-independent carrier molecules. I. The characteristics of the immune response to dinitrophenyl-lysine-substituted pneumococcal polysaccharide (SIII) and levan

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Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones.

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Idiotypic analysis of the response of C57BL/6 mice to the (4-hydroxy-3-nitrophenyl)acetyl group

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Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

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Antibody engineering for the analysis of affinity maturation of an anti-hapten response.

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A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.

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Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

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B cell development under the condition of allelic inclusion.

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Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

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A quasi-monoclonal mouse

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7 January 2021

Germinal centers without T cells

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7 January 2021

Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells

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FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen

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Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells

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Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival

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CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

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Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.

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Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes

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Positive and negative roles of the tyrosine kinase Lyn in B cell function

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Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

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Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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Inhibition of the B cell by CD22: a requirement for Lyn

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CD22 regulates thymus-independent responses and the lifespan of B cells.

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Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

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7 January 2021

The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation

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Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

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7 January 2021

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

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7 January 2021

Germinal centers develop oligoclonally

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7 January 2021

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

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7 January 2021

Molecular determinants of immunogenicity: the immunon model of immune response

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7 January 2021

The influence of antigen organization on B cell responsiveness

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7 January 2021

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

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7 January 2021

Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

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Dependence of germinal center B cells on expression of CD21/CD35 for survival.

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7 January 2021

Kinetic maturation of an immune response

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7 January 2021

Kinetic and affinity limits on antibodies produced during immune responses

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7 January 2021

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

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7 January 2021

B cells extract and present immobilized antigen: implications for affinity discrimination

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7 January 2021

Tolerogenic or immunogenic activity of hapten‐conjugated polysaccharides correlated with cellular localization

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7 January 2021

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

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HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

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7 January 2021

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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7 January 2021

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

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7 January 2021

Identifiers

DOI

10.1038/NI776

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28 November 2017

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