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The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2.
scientific article published in April 2002
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
title
The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author
Martin Turner
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
Josephine Meade
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Claire Fernandez
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
language of work or name
English
0 references
publication date
1 April 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
European Journal of Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
32
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
1029-1034
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
cites work
Examination of B lymphoid cell lines for membrane immunoglobulin-stimulated tyrosine phosphorylation and src-family tyrosine kinase mRNA expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Inhibition of the B cell by CD22: a requirement for Lyn
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Peripheral deletion of self-reactive B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1521-4141%28200204%2932%3A4%3C1029%3A%3AAID-IMMU1029%3E3.0.CO%3B2-M
retrieved
21 January 2018
Identifiers
DOI
10.1002/1521-4141(200204)32:4<1029::AID-IMMU1029>3.0.CO;2-M
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed ID
11920569
1 reference
stated in
Europe PubMed Central
PubMed ID
11920569
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11920569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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