(Q43972167)

28 November 2017

title

Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine (English)

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28 November 2017

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Christopher Banfield

1

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28 November 2017

Samir Gupta

2

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28 November 2017

Mark Marino

3

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28 November 2017

Josephine Lim

4

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28 November 2017

Melton Affrime

5

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28 November 2017

publication date

1 January 2002

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Clinical Pharmacokinetics

28 November 2017

published in

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28 November 2017

volume

41

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28 November 2017

issue

4

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28 November 2017

page(s)

311-318

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Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells

28 November 2017

cites work

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12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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12 December 2020

Desloratadine: A new, nonsedating, oral antihistamine

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12 December 2020

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

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12 December 2020

Cardiovascular safety of second-generation antihistamines

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12 December 2020

Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Drug-grapefruit juice interactions

1 reference

12 December 2020

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

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12 December 2020

Amounts and variation in grapefruit juice of the main components causing grapefruit-drug interaction

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12 December 2020

P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans

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12 December 2020

Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein

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12 December 2020

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

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12 December 2020

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

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12 December 2020

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects

1 reference

12 December 2020

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects.

1 reference

12 December 2020

Grapefruit juice-drug interactions

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12 December 2020

In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes

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12 December 2020

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

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12 December 2020

10.2165/00003088-200241040-00004

Identifiers

DOI

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Dimensions Publication ID

28 November 2017

1039317322

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Fatcat ID

release_hegyceav7jcfnlogywm6jqtgwe

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Fatcat

https://api.fatcat.wiki/v0/release/hegyceav7jcfnlogywm6jqtgwe

24 November 2022

mapped directly with Wikidata item

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