(Q43972710)

28 November 2017

3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists (English)

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12 May 2020

12

Charles F Zorumski

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12 May 2020

7

Ann Benz

1 reference

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12 May 2020

11

Douglas F Covey

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12 May 2020

author name string

Mingde Wang

1

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12 May 2020

Yejun He

2

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12 May 2020

Lawrence N Eisenman

3

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12 May 2020

Christopher Fields

4

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12 May 2020

Chun-Min Zeng

5

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12 May 2020

Jose Mathews

6

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12 May 2020

Tao Fu

8

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12 May 2020

Erik Zorumski

9

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12 May 2020

Joe Henry Steinbach

10

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12 May 2020

Steven Mennerick

13

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12 May 2020

language of work or name

English

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publication date

1 May 2002

1 reference

28 November 2017

Journal of Neuroscience

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12 May 2020

volume

22

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12 May 2020

issue

9

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12 May 2020

page(s)

3366-3375

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Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells.

12 May 2020

cites work

1 reference

12 December 2020

Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit

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12 December 2020

Effects of steroids on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by poly(A)+ RNA from mammalian brain and retina

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12 December 2020

Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids.

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12 December 2020

Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons

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12 December 2020

Shaping of IPSCs by endogenous calcineurin activity.

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12 December 2020

Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures.

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12 December 2020

Potentiation of gamma-aminobutyric-acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones

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12 December 2020

Neurosteroid analogues. 4. The effect of methyl substitution at the C-5 and C-10 positions of neurosteroids on electrophysiological activity at GABAA receptors.

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12 December 2020

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

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12 December 2020

Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor.

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12 December 2020

Neurosteroids act on recombinant human GABAA receptors

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12 December 2020

Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell culture

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12 December 2020

Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid

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12 December 2020

Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation

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12 December 2020

Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates

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12 December 2020

Pregnenolone sulfate modulates inhibitory synaptic transmission by enhancing GABA(A) receptor desensitization

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12 December 2020

Desensitized states prolong GABAA channel responses to brief agonist pulses.

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12 December 2020

GABAA receptor channels

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12 December 2020

5β-Pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex

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12 December 2020

Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency

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12 December 2020

Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites

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12 December 2020

How quickly can GABAA receptors open?

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12 December 2020

Recent developments in structure–activity relationships for steroid modulators of GABAA receptors

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12 December 2020

Epipregnanolone acts as a partial agonist on a common neurosteroid modulatory site of the GABA(A) receptor complex in avian CNS.

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12 December 2020

Differential antagonism by epipregnanolone of alphaxalone and pregnanolone potentiation of [3H]flunitrazepam binding suggests more than one class of binding site for steroids at GABAA receptors.

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12 December 2020

Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders

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12 December 2020

Enhancement of gamma-aminobutyric acidA receptor activity by alpha-chloralose.

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12 December 2020

Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission

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12 December 2020

Modulation of GABA(A) receptor function by neuroactive steroids: evidence for heterogeneity of steroid sensitivity of recombinant GABA(A) receptor isoforms.

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12 December 2020

Modulation of GABAA receptor-mediated IPSCs by neuroactive steroids in a rat hypothalamo-hypophyseal coculture model.

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12 December 2020

The inhibitory effects of allopregnanolone and pregnanolone on the population spike, evoked in the rat hippocampal CA1 stratum pyramidale in vitro, can be blocked selectively by epiallopregnanolone.

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12 December 2020

Passive and synaptic properties of hippocampal neurons grown in microcultures and in mass cultures

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12 December 2020

10.1523/JNEUROSCI.22-09-03366.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758359&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758359&resulttype=core&format=json

12 May 2020

1 reference