(Q43976134)

English

A simple method for the preparation of (5Z,8Z,11Z,14Z)-16-hydroxyeicosa-5,8,11,14-tetraenoic acid enantiomers and the corresponding 14,15-dehydro analogues: role of the 16-hydroxy group for the lipoxygenase reaction

scientific article published in July 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 November 2017

A simple method for the preparation of (5Z,8Z,11Z,14Z)-16-hydroxyeicosa-5,8,11,14-tetraenoic acid enantiomers and the corresponding 14,15-dehydro analogues: role of the 16-hydroxy group for the lipoxygenase reaction (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

1 reference

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5

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Hartmut Kuhn

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28 November 2017

author name string

Igor V Ivanov

1

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Europe PubMed Central

PubMed publication ID

28 November 2017

Stepan G Romanov

2

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Europe PubMed Central

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28 November 2017

Nataliya V Groza

3

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28 November 2017

Santosh Nigam

4

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28 November 2017

Galina I Myagkova

6

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28 November 2017

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publication date

1 July 2002

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28 November 2017

Bioorganic & Medicinal Chemistry

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28 November 2017

10

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PubMed publication ID

28 November 2017

7

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Europe PubMed Central

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28 November 2017

2335-2343

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Europe PubMed Central

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28 November 2017

Current problems with non-specific COX inhibitors

1 reference

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Lipid mediators in the pathophysiology of critical illness

1 reference

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Analysis of a specific oxygenation reaction of soybean lipoxygenase-1 with fatty acids esterified in phospholipids

1 reference

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Double dioxygenation of arachidonic acid by soybean lipoxygenase-1. Kinetics and regio-stereo specificities of the reaction steps

1 reference

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7 January 2021

based on heuristic

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Keto fatty acids not containing doubly allylic methylenes are lipoxygenase substrates.

1 reference

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7 January 2021

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Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation.

1 reference

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16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke

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16(R)-hydroxy-5,8,11,14-eicosatetraenoic acid, a new arachidonate metabolite in human polymorphonuclear leukocytes

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Asymmetric Reduction. A Convenient Method for the Reduction of Alkynyl Ketones

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Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: effect of the alcohol modifier.

1 reference

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Omega-oxidation impairs oxidizability of polyenoic fatty acids by 15-lipoxygenases: consequences for substrate orientation at the active site

1 reference

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Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis

1 reference

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The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action

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Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets

1 reference

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based on heuristic

inferred from DOI database lookup

Leukocyte 12-lipoxygenase: expression, purification, and investigation of the role of methionine residues in turnover-dependent inactivation and 5,8,11,14-eicosatetraynoic acid inhibition.

1 reference

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based on heuristic

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Lipoxygenase is irreversibly inactivated by the hydroperoxides formed from the enynoic analogues of linoleic acid

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0968-0896(02)00024-X

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

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