(Q43981311)

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Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel

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Europe PubMed Central

28 November 2017

Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel (English)

1 reference

Europe PubMed Central

28 November 2017

apoptotic process

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phosphorylation

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1 reference

based on heuristic

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author name string

Geertruida M Kolfschoten

1

1 reference

Europe PubMed Central

28 November 2017

Theresia M Hulscher

2

1 reference

Europe PubMed Central

28 November 2017

Monique C A Duyndam

3

1 reference

Europe PubMed Central

28 November 2017

Herbert M Pinedo

4

1 reference

Europe PubMed Central

28 November 2017

Epie Boven

5

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Europe PubMed Central

28 November 2017

language of work or name

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publication date

1 February 2002

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Europe PubMed Central

28 November 2017

Biochemical Pharmacology

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Europe PubMed Central

28 November 2017

63

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Europe PubMed Central

28 November 2017

4

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Europe PubMed Central

28 November 2017

733-743

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Europe PubMed Central

28 November 2017

The taxoids. Comparative clinical pharmacology and therapeutic potential

1 reference

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Dual cytotoxic mechanisms of submicromolar taxol on human leukemia HL-60 cells

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Induction of apoptosis by taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells

1 reference

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Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.

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Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

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Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line

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Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells

1 reference

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

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Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

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Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

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Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

1 reference

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Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

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7 January 2021

Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells

1 reference

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7 January 2021

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

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Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

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2-Methoxyestradiol-induced phosphorylation of Bcl-2: uncoupling from JNK/SAPK activation.

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Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells

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DDP-induced cytotoxicity is not influenced by p53 in nine human ovarian cancer cell lines with different p53 status.

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors

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Lack of correlation between mitotic arrest or apoptosis and antitumor effect of docetaxel

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Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

1 reference

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Interdigital cell death can occur through a necrotic and caspase-independent pathway.

1 reference

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Caspase-independent programmed cell death with necrotic morphology

1 reference

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7 January 2021

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

1 reference

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Caspase-independent cell killing by Fas-associated protein with death domain

1 reference

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BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

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Evidence against apoptosis as a major mechanism for reproductive cell death following treatment of cell lines with anti-cancer drugs

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7 January 2021

Identifiers

10.1016/S0006-2952(01)00895-4

1 reference

Europe PubMed Central

28 November 2017

1 reference

Europe PubMed Central

28 November 2017

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