(Q44006810)

English

Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity

scientific article published in May 2002

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

28 November 2017

Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity (English)

1 reference

Europe PubMed Central

28 November 2017

author name string

Alleyn T Plowright

1

1 reference

Europe PubMed Central

28 November 2017

Scott E Schaus

2

1 reference

Europe PubMed Central

28 November 2017

Andrew G Myers

3

1 reference

Europe PubMed Central

28 November 2017

publication date

1 May 2002

1 reference

Europe PubMed Central

28 November 2017

Chemistry and Biology

1 reference

Europe PubMed Central

28 November 2017

9

1 reference

Europe PubMed Central

28 November 2017

5

1 reference

Europe PubMed Central

28 November 2017

607-618

1 reference

Europe PubMed Central

28 November 2017

New antibiotics, saframycins A, B, C, D and E.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The structure of a novel antitumor antibiotic, saframycin A

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mode of action of saframycin A, a novel heterocyclic quinone antibiotic. Inhibition of RNA synthesis in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-activity relationships of saframycins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of binding and single-strand scission of deoxyribonucleic acid by the antitumor antibiotics saframycins A and C

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mode of action of saframycin antitumor antibiotics: sequence selectivities in the covalent binding of saframycins A and S to deoxyribonucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA sequence selectivities in the covalent bonding of antibiotic saframycins Mx1, Mx3, A, and S deduced from MPE.Fe(II) footprinting and exonuclease III stop assays

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Computer simulation of the binding of saframycin A to d (GATGCATC)2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Bioactive compounds from aquatic and terrestrial sources

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ecteinascidins: Putative Biosynthetic Precursors and Absolute Stereochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ecteinascidin-743: a marine-derived compound in advanced, pretreated sarcoma patients--preliminary evidence of activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased DNA Binding Specificity for Antitumor Ecteinascidin 743 through Protein−DNA Interactions?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Antitumor activity- and gene expression-based profiling of ecteinascidin Et 743 and phthalascidin Pt 650.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and evaluation of bishydroquinone derivatives of (-)-saframycin A: identification of a versatile molecular template imparting potent antiproliferative activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Exploring the metabolic and genetic control of gene expression on a genomic scale

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Yeast microarrays for genome wide parallel genetic and gene expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide expression monitoring in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomewide studies of histone deacetylase function in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide expression patterns in Saccharomyces cerevisiae: comparison of drug treatments and genetic alterations affecting biosynthesis of ergosterol

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in LIS1 (ERG6) gene confer increased sodium and lithium uptake in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Yeast multidrug resistance: the PDR network.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Saccharomyces cerevisiae SSB1 protein and its relationship to nucleolar RNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Starting up yeast glycolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A yeast phosphofructokinase insensitive to the allosteric activator fructose 2,6-bisphosphate. Glycolysis/metabolic regulation/allosteric control

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The H2O2 stimulon in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytosolic Hsp70s are involved in the transport of aminopeptidase 1 from the cytoplasm into the vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Early steps in assembly of the yeast vacuolar H+-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Remodeling of yeast genome expression in response to environmental changes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Alteration in the choice of DNA repair pathway with increasing sequence selective DNA alkylation in the minor groove

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle regulation of yeast histone mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA arrays for analysis of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900137-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1074-5521(02)00137-0

1 reference

Europe PubMed Central

28 November 2017

1 reference

Europe PubMed Central

28 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44006810&oldid=2105584480"