(Q44011524)

28 November 2017

Immunotherapy targeting 4-1BB and its ligand (English)

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28 November 2017

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Dass S Vinay

1

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28 November 2017

Byoung S Kwon

series ordinal

2

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28 November 2017

1 January 2006

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International Journal of Hematology

28 November 2017

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28 November 2017

83

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28 November 2017

23-28

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28 November 2017

1

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https://scigraph.springernature.com/pub.10.1532/ijh97.05125

28 November 2017

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cites work

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

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12 December 2020

Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy

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12 December 2020

Anti-CD137 antibodies in the treatment of autoimmune disease and cancer

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12 December 2020

Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen

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12 December 2020

Potential role of 4-1BB in T cell activation. Comparison with the costimulatory molecule CD28

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12 December 2020

Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3

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12 December 2020

4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells

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12 December 2020

A novel adenovirus expressing human 4-1BB ligand enhances antitumor immunity

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12 December 2020

In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway

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12 December 2020

Signalling pathways of the TNF superfamily: a double-edged sword

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12 December 2020

Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal

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12 December 2020

CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

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12 December 2020

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

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12 December 2020

Effector CD8 T cells possess suppressor function after 4-1BB and Toll-like receptor triggering

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12 December 2020

Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis

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12 December 2020

The TNF and TNF receptor superfamilies: integrating mammalian biology

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12 December 2020

Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells

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12 December 2020

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

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12 December 2020

Analysis of costimulation by 4-1BBL, CD40L, and B7 in graft rejection by gene expression profiles.

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12 December 2020

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

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12 December 2020

NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

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12 December 2020

Inducible T cell antigen 4-1BB. Analysis of expression and function

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12 December 2020

Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4

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12 December 2020

4-1BB-mediated immunotherapy of rheumatoid arthritis.

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12 December 2020

4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner.

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12 December 2020

Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB.

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12 December 2020

Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice

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12 December 2020

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

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12 December 2020

Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis.

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12 December 2020

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

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12 December 2020

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

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12 December 2020

4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses

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12 December 2020

Regulation of dendritic cell function by NK cells: mechanisms underlying the synergism in the combination therapy of IL-12 and 4-1BB activation

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12 December 2020

Therapeutic vaccination with tumor cells that engage CD137.

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12 December 2020

The signaling adaptors and pathways activated by TNF superfamily

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12 December 2020

Murine keratocytes function as antigen-presenting cells.

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12 December 2020

Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines

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12 December 2020

4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12.

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12 December 2020

Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival

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12 December 2020

Role of 4-1BB in immune responses.

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12 December 2020

Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56lck1.

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12 December 2020

Immune responses in 4-1BB (CD137)-deficient mice

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12 December 2020

Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus.

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12 December 2020

Cutting edge: Expression of functional CD137 receptor by dendritic cells

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12 December 2020

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

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12 December 2020

Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity

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12 December 2020

Tumor Expression of 4-1BB Ligand Sustains Tumor Lytic T Cells

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12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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12 December 2020

Regulation of follicular dendritic cell networks by activated T cells: the role of CD137 signaling.

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12 December 2020

Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

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12 December 2020

4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination

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12 December 2020

Identifiers

DOI

10.1532/IJH97.05125

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Dimensions Publication ID

28 November 2017

1042041498

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Fatcat ID

release_pjk5bjvy5fbydpije6xjlwuyd4

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Fatcat

https://api.fatcat.wiki/v0/release/pjk5bjvy5fbydpije6xjlwuyd4

24 November 2022

mapped directly with Wikidata item

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