(Q44014270)

English

Regulation of mu-opioid receptors, G-protein-coupled receptor kinases and beta-arrestin 2 in the rat brain after chronic opioid receptor antagonism.

scientific article published in January 2002

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044452%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Regulation of mu-opioid receptors, G-protein-coupled receptor kinases and beta-arrestin 2 in the rat brain after chronic opioid receptor antagonism (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12044452%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

G protein-coupled receptor

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0 references

1

1 reference

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9 November 2019

María A Hurlé

6

1 reference

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9 November 2019

author name string

A Pazos

2

1 reference

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9 November 2019

J Flórez

3

1 reference

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9 November 2019

F J Ayesta

4

1 reference

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9 November 2019

V Santana

5

1 reference

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9 November 2019

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publication date

1 January 2002

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9 November 2019

1 reference

Europe PubMed Central

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9 November 2019

112

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9 November 2019

2

1 reference

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9 November 2019

345-353

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9 November 2019

Control of breathing in experimental anemia

1 reference

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Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

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Enhanced morphine analgesia in mice lacking beta-arrestin 2

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Regulation of peripheral cannabinoid receptor CB2 phosphorylation by the inverse agonist SR 144528. Implications for receptor biological responses

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G-protein coupling of mu-opioid receptors (OP3): elevated basal signalling activity

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A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

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Autoradiographic mapping of mu-opioid receptors during opiate tolerance and supersensitivity in the rat central nervous system.

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Calcium channel modulation by dihydropyridines modifies sufentanil-induced antinociception in acute and tolerant conditions.

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Changes in the expression of G protein-coupled receptor kinases and beta-arrestin 2 in rat brain during opioid tolerance and supersensitivity.

1 reference

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7 January 2021

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Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes

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7 January 2021

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Molecular mechanisms and regulation of opioid receptor signaling

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Agonist-independent regulation of constitutively active G-protein-coupled receptors

1 reference

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Up-regulation of a constitutively active form of the beta2-adrenoceptor by sustained treatment with inverse agonists but not antagonists

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Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

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7 January 2021

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Inability of an opioid antagonist lacking negative intrinsic activity to induce opioid receptor up-regulation in vivo

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Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation

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Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists

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7 January 2021

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Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

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7 January 2021

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Regulation of G protein-coupled receptor kinase 2 in brains of opiate-treated rats and human opiate addicts.

1 reference

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7 January 2021

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Protein kinases that phosphorylate activated G protein-coupled receptors.

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Potentiation of acute opioid-induced respiratory depression and reversal of tolerance by the calcium antagonist nimodipine in awake rats.

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Recommended drug treatment strategies for the alcoholic patient

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7 January 2021

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Chronic morphine administration increases beta-adrenergic receptor kinase (beta ARK) levels in the rat locus coeruleus

1 reference

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7 January 2021

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Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels

1 reference

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7 January 2021

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A cluster of Ser/Thr residues at the C-terminus of mu-opioid receptor is required for G protein-coupled receptor kinase 2-mediated desensitization

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Constitutive mu opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence

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Opioid receptor upregulation and supersensitivity in mice: effect of morphine sensitivity

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A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types

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Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness

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