(Q44020919)

29 November 2017

Probing the specificity of a trypanosomal aromatic alpha-hydroxy acid dehydrogenase by site-directed mutagenesis (English)

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29 November 2017

3

Andrej Sali

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author name string

Javier Vernal

1

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29 November 2017

András Fiser

2

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29 November 2017

Miklós Müller

4

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29 November 2017

Juan José Cazzulo

5

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29 November 2017

Cristina Nowicki

6

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29 November 2017

language of work or name

English

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publication date

1 April 2002

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Biochemical and Biophysical Research Communications

29 November 2017

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29 November 2017

293

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29 November 2017

633-639

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29 November 2017

1

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describes a project that uses

29 November 2017

site-directed mutagenesis

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based on heuristic

inferred from title

cites work

Malate dehydrogenase: a model for structure, evolution, and catalysis

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The structural basis of molecular adaptation

7 January 2021

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Purification and partial structural and kinetic characterization of an aromatic L-alpha-hydroxy acid dehydrogenase from epimastigotes of Trypanosoma cruzi.

7 January 2021

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The NAD-linked aromatic alpha-hydroxy acid dehydrogenase from Trypanosoma cruzi. A new member of the cytosolic malate dehydrogenases group without malate dehydrogenase activity

7 January 2021

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Sequencing and heterologous expression of a cytosolic-type malate dehydrogenase of Trypanosoma brucei

7 January 2021

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A family of highly conserved glycosomal 2-hydroxyacid dehydrogenases from Phytomonas sp.

7 January 2021

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Lactic dehydrogenase in Trichomonas vaginalis.

7 January 2021

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Convergent evolution of Trichomonas vaginalis lactate dehydrogenase from malate dehydrogenase

7 January 2021

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Structural adaptations of lactate dehydrogenase isozymes

7 January 2021

1 reference

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Amino acid sequence homology among the 2-hydroxy acid dehydrogenases: mitochondrial and cytoplasmic malate dehydrogenases form a homologous system with lactate dehydrogenase

7 January 2021

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Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-A resolution

7 January 2021

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Evolutionary relationships among the malate dehydrogenases

7 January 2021

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The importance of arginine 102 for the substrate specificity of Escherichia coli malate dehydrogenase

7 January 2021

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Structure of porcine heart cytoplasmic malate dehydrogenase: combining X-ray diffraction and chemical sequence data in structural studies

7 January 2021

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Crystal structure of a ternary complex of Escherichia coli malate dehydrogenase citrate and NAD at 1.9 A resolution

7 January 2021

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Substitution of the amino acid at position 102 with polar and aromatic residues influences substrate specificity of lactate dehydrogenase.

7 January 2021

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Rational construction of a 2-hydroxyacid dehydrogenase with new substrate specificity.

7 January 2021

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A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework

7 January 2021

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Cloning, sequencing, and expression in Escherichia coli of the gene coding for malate dehydrogenase of the extremely halophilic archaebacterium Haloarcula marismortui

7 January 2021

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Stringency of substrate specificity of Escherichia coli malate dehydrogenase

7 January 2021

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Malate/lactate dehydrogenase in mollicutes: evidence for a multienzyme protein

7 January 2021

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Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases

7 January 2021

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Comparative protein modelling by satisfaction of spatial restraints

7 January 2021

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Recognition of errors in three-dimensional structures of proteins

7 January 2021

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PROCHECK: a program to check the stereochemical quality of protein structures

7 January 2021

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Iterated profile searches with PSI-BLAST--a tool for discovery in protein databases

7 January 2021

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Modeling of loops in protein structures

7 January 2021

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

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From malate dehydrogenase to phenyllactate dehydrogenase. Incorporation of unnatural amino acids to generate an improved enzyme-catalyzed activity

7 January 2021

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Studies on the metabolism of the protozoa. 5. Metabolism of the parasitic flagellate Trichomonas foetus

7 January 2021

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10.1016/S0006-291X(02)00270-X

7 January 2021

Identifiers

DOI

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29 November 2017

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