(Q44022916)

29 November 2017

Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels (English)

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29 November 2017

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Akira Nakajima

1

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29 November 2017

Kiyofumi Yamada

2

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29 November 2017

Li-Bo Zou

3

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29 November 2017

Yijin Yan

4

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29 November 2017

Makoto Mizuno

5

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29 November 2017

Toshitaka Nabeshima

6

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29 November 2017

language of work or name

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1 June 2002

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Free Radical Biology and Medicine

29 November 2017

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29 November 2017

32

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29 November 2017

12

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29 November 2017

1324-1332

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Oxygen free radicals and brain dysfunction

29 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Free radicals in brain metabolism and pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Cytotoxicity and metabolism of 4-hydroxy-2-nonenal and 2-nonenal in H2O2-resistant cell lines. Do aldehydic by-products of lipid peroxidation contribute to oxidative stress?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by mitochondria isolated from rat kidney cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Parkinson's disease: a disorder due to nigral glutathione deficiency?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Interleukin-1 is an astroglial growth factor in the developing brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Cytokine regulation of neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Interleukin-2 enhances the viability of primary cultured rat neocortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Protective effect of interleukin-6 against the death of PC12 cells caused by serum deprivation or by the addition of a calcium ionophore

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Possible involvement of catalase in the protective effect of interleukin-6 against 6-hydroxydopamine toxicity in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Gamma-glutamylcysteine synthetase activity in human lung epithelial (A549) cells: factors influencing its measurement

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Identification of a novel cysteine string protein variant and expression of cysteine string proteins in non-neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Mammalian oviduct and protection against free oxygen radicals: expression of genes encoding antioxidant enzymes in human and mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Dexamethasone, but not stress, induce measurable changes of mitochondrial benzodiazepine receptor mRNA levels in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis).

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

1 reference

7 January 2021

Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Animal models of Alzheimer's disease and evaluation of anti-dementia drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Role of nerve growth factor in oxidant homeostasis: glutathione metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Decreased interleukin-6 level in the cerebrospinal fluid of patients with Alzheimer-type dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

Patterns of asymmetry do not change over the course of idiopathic parkinsonism: implications for pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900845-6

7 January 2021

10.1016/S0891-5849(02)00845-6

Identifiers

DOI

1 reference

29 November 2017

1 reference