(Q44042205)

29 November 2017

Constitutive activation of NF-kappaB in Ki-ras-transformed prostate epithelial cells (English)

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29 November 2017

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Bo-Yeon Kim

1

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29 November 2017

Richard B Gaynor

2

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29 November 2017

Kyung Song

3

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29 November 2017

Anatoly Dritschilo

4

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29 November 2017

Mira Jung

5

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29 November 2017

language of work or name

English

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publication date

1 July 2002

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29 November 2017

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29 November 2017

21

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29 November 2017

29

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29 November 2017

4490-4497

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describes a project that uses

29 November 2017

267B1

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267B1/Ki-ras

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exact match

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205547

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cites work

Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Nuclear IkappaBbeta maintains persistent NF-kappaB activation in HIV-1-infected myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

R-Ras3, a brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Molecular determinants of NF-kappaB-inducing kinase action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Neoplastic transformation of a human prostate epithelial cell line by the v-Ki-ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Structure, regulation and function of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Frequent activation of the Ki-ras oncogene at codon 12 inN-methyl-N-nitrosourea-induced rat prostate adenocarcinomas and neurogenic sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

The Akt proto-oncogene links Ras to Pak and cell survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

NAK is an IkappaB kinase-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

The murine N-ras gene is not essential for growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

I kappa B proteins: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Sulindac inhibits activation of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Prevalence of ras gene mutations in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

Ras controls tumor necrosis factor receptor-associated factor (TRAF)6-dependent induction of nuclear factor-kappa b. Selective regulation through receptor signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

inferred from DOI database lookup

7 January 2021

based on heuristic

Nuclear factor kappa B activity in response to oxidants and antioxidants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205547

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205547

1 reference

29 November 2017

1 reference