(Q44045526)

29 November 2017

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title

How can we realize the promise of personalized antidepressant medicines? (English)

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29 November 2017

Florian Holsboer

1

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29 November 2017

language of work or name

English

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publication date

16 July 2008

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Nature Reviews Neuroscience

29 November 2017

published in

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29 November 2017

volume

9

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29 November 2017

issue

8

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29 November 2017

page(s)

638-646

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Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial

29 November 2017

cites work

1 reference

Genome-based pharmacogenetics and the pharmaceutical industry

21 January 2018

1 reference

Pharmacogenetics and the practice of medicine

31 March 2020

1 reference

Pharmacogenomics and antidepressant drugs

31 March 2020

1 reference

Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study.

31 March 2020

1 reference

HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies

31 March 2020

1 reference

The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: alternative biallelic variation in rhesus monkeys. Rapid communication.

31 March 2020

1 reference

The influence of Serotonin Transporter Promoter Polymorphism (SERTPR) and other polymorphisms of the serotonin pathway on the efficacy of antidepressant treatments

31 March 2020

1 reference

Analysis of association between the serotonin transporter and antidepressant response in a large clinical sample

31 March 2020

1 reference

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression

31 March 2020

1 reference

Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

31 March 2020

1 reference

The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

31 March 2020

1 reference

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

31 March 2020

1 reference

Blood—Brain Barrier Genomics

31 March 2020

1 reference

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression

31 March 2020

1 reference

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

31 March 2020

1 reference

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

31 March 2020

1 reference

Switching from repression to activation: microRNAs can up-regulate translation

31 March 2020

1 reference

MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells

31 March 2020

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

31 March 2020

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

31 March 2020

1 reference

Conserved non-genic sequences - an unexpected feature of mammalian genomes

31 March 2020

1 reference

Megabase deletions of gene deserts result in viable mice

31 March 2020

1 reference

Global variation in copy number in the human genome

31 March 2020

1 reference

Psoriasis is associated with increased beta-defensin genomic copy number

31 March 2020

1 reference

Molecular studies of major depressive disorder: the epigenetic perspective

31 March 2020

1 reference

Epigenetic regulation in psychiatric disorders

31 March 2020

1 reference

Translating the Histone Code

31 March 2020

1 reference

Histone methylation in transcriptional control

31 March 2020

1 reference

Acetylation and chromosomal functions.

31 March 2020

1 reference

Rad6-dependent ubiquitination of histone H2B in yeast

31 March 2020

1 reference

Histone modifications: Now summoning sumoylation

31 March 2020

1 reference

RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia

31 March 2020

1 reference

SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

31 March 2020

1 reference

Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli

31 March 2020

1 reference

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

31 March 2020

1 reference

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

31 March 2020

1 reference

Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life.

31 March 2020

1 reference

The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies

31 March 2020

1 reference

Epigenetic differences arise during the lifetime of monozygotic twins

31 March 2020

1 reference

The emerging landscape of breast cancer susceptibility

31 March 2020

1 reference

Can neuroscience be integrated into the DSM-V?

31 March 2020

1 reference

Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway.

31 March 2020

1 reference

Critical appraisal of DNA microarrays in psychiatric genomics.

31 March 2020

1 reference

Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients

31 March 2020

1 reference

The corticosteroid receptor hypothesis of depression

31 March 2020

1 reference

Stress-induced changes in primate prefrontal profiles of gene expression

31 March 2020

1 reference

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

31 March 2020

1 reference

Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety.

31 March 2020

1 reference

Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.

31 March 2020

1 reference

Protein biomarkers in a mouse model of extremes in trait anxiety

31 March 2020

1 reference

Epigenetic programming by maternal behavior

31 March 2020

1 reference

Proteomics and the Human Metabolome Project

31 March 2020

1 reference

Metabolite profiling: from diagnostics to systems biology

31 March 2020

1 reference

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

31 March 2020

1 reference

Metabolomic mapping of atypical antipsychotic effects in schizophrenia.

31 March 2020

1 reference

A role for fMRI in optimizing CNS drug development

31 March 2020

1 reference

Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group

31 March 2020

1 reference

Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study

31 March 2020

1 reference

An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology

31 March 2020

1 reference

High-speed imaging reveals neurophysiological links to behavior in an animal model of depression

31 March 2020

1 reference

Subgenual prefrontal cortex abnormalities in mood disorders

31 March 2020

1 reference

Pharmaco-EEG profile of maroxepine: third example to discuss the predictive value of pharmaco-electroencephalography in early human pharmacological evaluations of psychoactive drugs

31 March 2020

1 reference

Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study

31 March 2020

1 reference

Changes in brain function (quantitative EEG cordance) during placebo lead-in and treatment outcomes in clinical trials for major depression

31 March 2020

1 reference

Changes in QEEG prefrontal cordance as a predictor of response to antidepressants in patients with treatment resistant depressive disorder: a pilot study

31 March 2020

1 reference

Early changes in prefrontal activity characterize clinical responders to antidepressants

31 March 2020

1 reference

The promise of the quantitative electroencephalogram as a predictor of antidepressant treatment outcomes in major depressive disorder

31 March 2020

1 reference

From early to late adulthood. Changes in EEG sleep of depressed patients and healthy volunteers

31 March 2020

1 reference

Electroencephalographic sleep profiles in treatment course and long-term outcome of major depression: association with DEX/CRH-test response

31 March 2020

1 reference

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

31 March 2020

1 reference

Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients

31 March 2020

1 reference

Stress and the brain: from adaptation to disease

31 March 2020

1 reference

Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?

31 March 2020

1 reference

New approaches to antidepressant drug discovery: beyond monoamines

31 March 2020

1 reference

From monoamines to genomic targets: a paradigm shift for drug discovery in depression

31 March 2020

1 reference

Towards a theory of biological robustness

31 March 2020

1 reference

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment

31 March 2020

1 reference

Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in japanese depressed patients

31 March 2020

1 reference

Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder.

31 March 2020

1 reference

Serotonin receptor 2A gene polymorphism (-1438A/G) and short-term treatment response to citalopram

31 March 2020

1 reference

Investigation of serotonin-related genes in antidepressant response

31 March 2020

1 reference

Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort

31 March 2020

1 reference

A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression

31 March 2020

1 reference

SSRIs antidepressant activity is influenced by G beta 3 variants

31 March 2020

1 reference

Evidence for an association between a G-protein beta3-gene variant with depression and response to antidepressant treatment

31 March 2020

1 reference

Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans

31 March 2020

1 reference

Association study of corticotropin-releasing hormone receptor1 gene polymorphisms and antidepressant response in major depressive disorders

31 March 2020

1 reference

Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients

31 March 2020

1 reference

Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder

31 March 2020

1 reference

Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder.

31 March 2020

1 reference

Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders

31 March 2020

1 reference

Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response

31 March 2020

1 reference

The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings

31 March 2020

1 reference

The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients

31 March 2020

1 reference

Analysis of COMT gene (Val 158 Met polymorphism) in the clinical response to SSRIs in depressive patients of European origin

31 March 2020

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The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression

31 March 2020

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Association of the COMT val158met variant with antidepressant treatment response in major depression

31 March 2020

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Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response

31 March 2020

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Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRN2453

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29 November 2017

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