(Q44047059)

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Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis

scientific article published in February 2008

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Europe PubMed Central

PubMed publication ID

29 November 2017

Natural killer T cells exacerbate liver injury in a transforming growth factor beta receptor II dominant-negative mouse model of primary biliary cirrhosis (English)

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Europe PubMed Central

PubMed publication ID

29 November 2017

liver cirrhosis

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primary biliary cholangitis

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Mitchell Kronenberg

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Mitchell Kronenberg

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Europe PubMed Central

PubMed publication ID

29 November 2017

M. Eric Gershwin

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M Eric Gershwin

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29 November 2017

Aftab A. Ansari

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Aftab A Ansari

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29 November 2017

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Zhe-Xiong Lian

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29 November 2017

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Yuki Moritoki

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29 November 2017

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Shang-An Shu

1 reference

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29 November 2017

Richard Flavell

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Richard A Flavell

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29 November 2017

author name string

Ya-Hui Chuang

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Europe PubMed Central

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29 November 2017

Guo-Xiang Yang

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29 November 2017

William M Ridgway

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29 November 2017

Bin Gao

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29 November 2017

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publication date

1 February 2008

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29 November 2017

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29 November 2017

47

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29 November 2017

2

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29 November 2017

571-580

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Europe PubMed Central

PubMed publication ID

29 November 2017

Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice

1 reference

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IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners

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Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations.

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Going both ways: immune regulation via CD1d-dependent NKT cells

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Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

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Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black x New Zealand White)F1 mice

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Age-associated augmentation of the synthetic ligand- mediated function of mouse NK1.1 ag(+) T cells: their cytokine production and hepatotoxicity in vivo and in vitro

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IL-2 receptor alpha deficiency and features of primary biliary cirrhosis

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Primary biliary cirrhosis: an orchestrated immune response against epithelial cells

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New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis

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Primary biliary cirrhosis

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Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells

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Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis

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Immunohistochemical localization of antigen presenting cells in liver from patients with primary biliary cirrhosis; highly restricted distribution of CD83-positive activated dendritic cells

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Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis

1 reference

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7 January 2021

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Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis

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7 January 2021

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Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis

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Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis

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AMA production in primary biliary cirrhosis is promoted by the TLR9 ligand CpG and suppressed by potassium channel blockers

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Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium

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Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer

1 reference

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7 January 2021

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Increased CD1d expression on small bile duct epithelium and epithelioid granuloma in livers in primary biliary cirrhosis

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Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis

1 reference

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7 January 2021

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Critical contribution of liver natural killer T cells to a murine model of hepatitis

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IL-2 receptor alpha(-/-) mice and the development of primary biliary cirrhosis

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Developmental program of mouse Valpha14i NKT cells

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

1 reference

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7 January 2021

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NKT cells: what's in a name?

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Toward an understanding of NKT cell biology: progress and paradoxes

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CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

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Recognition of bacterial glycosphingolipids by natural killer T cells

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Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

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How a T cell sees sugar

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Mechanism of CD1d-restricted natural killer T cell activation during microbial infection.

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Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

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Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

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Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

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CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases

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Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis

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Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

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NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

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Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

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Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

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In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset

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Cytokine profile in the liver of primary biliary cirrhosis

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Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relatives

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Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

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Sequential production of interferon-gamma by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of alpha -galactosylceramide

1 reference

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The X and why of xenobiotics in primary biliary cirrhosis

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10.1002/HEP.22052

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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