(Q44057933)

29 November 2017

title

Synthesis and characterization of a catalytic antibody-HPMA copolymer-Conjugate as a tool for tumor selective prodrug activation (English)

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29 November 2017

1

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29 November 2017

Holger N Lode

3

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author name string

Wolfgang Wrasidlo

series ordinal

2

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29 November 2017

Doron Shabat

series ordinal

4

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29 November 2017

language of work or name

English

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publication date

1 September 2002

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Bioorganic & Medicinal Chemistry

29 November 2017

published in

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29 November 2017

volume

10

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29 November 2017

issue

9

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29 November 2017

page(s)

3023-3029

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Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro

29 November 2017

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Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine

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Antibody directed enzyme prodrug therapy (ADEPT). A review of some theoretical, experimental and clinical aspects

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Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate

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Multiple event activation of a generic prodrug trigger by antibody catalysis

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Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing

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Prodrug activation via catalytic antibodies

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Synthesis and characterization of monoclonal antibody-beta-lactamase conjugates

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Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates

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Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene

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Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators

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7 January 2021

10.1016/S0968-0896(02)00156-6

Identifiers

DOI

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29 November 2017

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