(Q44058261)

29 November 2017

Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity (English)

1 reference

29 November 2017

Hae-Seong Yoon

1

1 reference

29 November 2017

Terrence J Monks

2

1 reference

29 November 2017

Jeffrey I Everitt

3

1 reference

29 November 2017

Cheryl L Walker

4

1 reference

29 November 2017

Serrine S Lau

5

1 reference

29 November 2017

1 August 2002

1 reference

American Journal of Physiology - Renal Physiology

29 November 2017

1 reference

29 November 2017

283

1 reference

29 November 2017

F262-70

1 reference

29 November 2017

2

1 reference

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

29 November 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

The toxicology of hydroquinone--relevance to occupational and environmental exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Screening of tobacco smoke constituents for mutagenicity using the Ames' test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Increased susceptibility to in vitro transformation of cells carrying the Eker tumor susceptibility mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Immunochemical analysis of quinol-thioether-derived covalent protein adducts in rodent species sensitive and resistant to quinol-thioether-mediated nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homolog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Methyl tert-butyl ether causes alpha2u-globulin nephropathy and enhanced renal cell proliferation in male Fischer-344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Mutagenicity of polycyclic aromatic hydrocarbons and quinones on Salmonella typhimurium TA97.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Induction of Renal Cell Tumors in Rats and Mice, and Enhancement of Hepatocellular Tumor Development in Mice after Long-term Hydroquinone Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Identification and characterization of the tuberous sclerosis gene on chromosome 16

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Stress- and growth-related gene expression are independent of chemical-induced prostaglandin E(2) synthesis in renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Molecular genetics of renal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Transformation of kidney epithelial cells by a quinol thioether via inactivation of the tuberous sclerosis-2 tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

A Dominant Gene for Renal Adenomas in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00261.2001

10.1152/AJPRENAL.00261.2001

21 January 2018

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DOI

0 references

1 reference