(Q44061426)

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2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

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scholarly article

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Europe PubMed Central

29 November 2017

2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors (English)

1 reference

Europe PubMed Central

29 November 2017

Richard L Mackman

1

object named as

Richard L Mackman

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Europe PubMed Central

29 November 2017

author name string

Hon C Hui

2

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29 November 2017

J Guy Breitenbucher

3

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29 November 2017

Bradley A Katz

4

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29 November 2017

Christine Luong

5

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29 November 2017

Arnold Martelli

6

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29 November 2017

Danny McGee

7

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29 November 2017

Kesavan Radika

8

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29 November 2017

Martin Sendzik

9

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29 November 2017

Jeffrey R Spencer

10

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29 November 2017

Paul A Sprengeler

11

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29 November 2017

James Tario

12

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29 November 2017

Erik Verner

13

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29 November 2017

Jing Wang

14

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29 November 2017

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publication date

1 August 2002

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29 November 2017

Bioorganic & Medicinal Chemistry Letters

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29 November 2017

12

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29 November 2017

15

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29 November 2017

2019-2022

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29 November 2017

The urokinase-type plasminogen activator system in cancer metastasis: a review

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Urokinase-type plasminogen activator (uPA) and its receptor (CD87): a new target in tumor invasion and metastasis

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Antibodies to plasminogen activator inhibit human tumor metastasis

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Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA).

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Development of serine protease inhibitors displaying a multicentered short (<2.3 A) hydrogen bond binding mode: inhibitors of urokinase-type plasminogen activator and factor Xa.

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Maximum effect of urokinase plasminogen activator inhibitors in the control of invasion and metastasis of rat mammary cancer

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A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site

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An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes

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Exploiting subsite S1 of trypsin-like serine proteases for selectivity: potent and selective inhibitors of urokinase-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900311-6

7 January 2021

based on heuristic

inferred from DOI database lookup

Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets

1 reference

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based on heuristic

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Crystal structure of the catalytic domain of human plasmin complexed with streptokinase

1 reference

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Identifiers

10.1016/S0960-894X(02)00311-6

1 reference

Europe PubMed Central

29 November 2017

1 reference

Europe PubMed Central

29 November 2017

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