(Q44078419)

29 November 2017

title

Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surface (English)

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29 November 2017

David B Cleary

1

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29 November 2017

Toni A Trumbo

series ordinal

2

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29 November 2017

Muriel C Maurer

series ordinal

3

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29 November 2017

language of work or name

English

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publication date

1 July 2002

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Archives of Biochemistry and Biophysics

29 November 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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29 November 2017

volume

403

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29 November 2017

issue

2

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29 November 2017

page(s)

179-188

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How the protease thrombin talks to cells

29 November 2017

cites work

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Domains specifying thrombin–receptor interaction

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Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

7 January 2021

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Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate

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Molecular mapping of thrombin-receptor interactions

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The dual role of thrombin's anion-binding exosite-I in the recognition and cleavage of the protease-activated receptor 1

7 January 2021

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Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage

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A dual thrombin receptor system for platelet activation

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Cloning and characterization of human protease-activated receptor 4

7 January 2021

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Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

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Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets

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Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin

7 January 2021

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Solution structure of a platelet receptor peptide bound to bovine alpha-thrombin

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On the active site of proteases. 3. Mapping the active site of papain; specific peptide inhibitors of papain

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Examining thrombin hydrolysis of the factor XIII activation peptide segment leads to a proposal for explaining the cardioprotective effects observed with the factor XIII V34L mutation

7 January 2021

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TITRATION BEHAVIOR OF BOVINE THROMBIN

7 January 2021

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

7 January 2021

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Selective loss of fibrinogen clotting in a loop-less thrombin

7 January 2021

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Use of the Transferred Nuclear Overhauser Effect To Determine the Conformations of Ligands Bound to Proteins

7 January 2021

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Thrombin hydrolysis of V29F and V34L mutants of factor XIII (28-41) reveals roles of the P(9) and P(4) positions in factor XIII activation

7 January 2021

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Thrombin-bound structures of designed analogs of human fibrinopeptide A determined by quantitative transferred NOE spectroscopy: a new structural basis for thrombin specificity

7 January 2021

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Interaction of thrombin and fibrinogen and the polymerization of fibrin monomer

7 January 2021

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A player of many parts: the spotlight falls on thrombin's structure.

7 January 2021

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Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

7 January 2021

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7 January 2021

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Mechanism of action of thrombin on fibrinogen. Direct evidence for the involvement of phenylalanine at position P9

7 January 2021

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Amino acid sequence studies on the .alpha. chain of human fibrinogen. Overlapping sequences providing the complete sequence

7 January 2021

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Characterization of the gene for the a subunit of human factor XIII (plasma transglutaminase), a blood coagulation factor

7 January 2021

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Characterization of the kinetic pathway for fibrin promotion of alpha-thrombin-catalyzed activation of plasma factor XIII

7 January 2021

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Interactions of factor XIII with fibrin as substrate and cofactor

7 January 2021

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10.1016/S0003-9861(02)00220-5

7 January 2021

Identifiers

DOI

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29 November 2017

1 reference