(Q44081130)

29 November 2017

ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis (English)

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29 November 2017

Andersen JL

1

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29 November 2017

Zimmerman ES

2

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29 November 2017

DeHart JL

3

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29 November 2017

Murala S

4

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29 November 2017

Ardon O

5

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29 November 2017

Blackett J

6

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29 November 2017

Chen J

7

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29 November 2017

Planelles V

8

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29 November 2017

language of work or name

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1 April 2005

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Cell Death & Differentiation

29 November 2017

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29 November 2017

12

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29 November 2017

4

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29 November 2017

326-334

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401565

29 November 2017

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cites work

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.

1 reference

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7 January 2021

Roles of p53 and caspases in the induction of cell cycle arrest and apoptosis by HIV-1 vpr

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Comparison of cell cycle arrest, transactivation, and apoptosis induced by the simian immunodeficiency virus SIVagm and human immunodeficiency virus type 1 vpr genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

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7 January 2021

Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency Syndrome

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7 January 2021

The human immunodeficiency virus: infectivity and mechanisms of pathogenesis

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7 January 2021

Long-term cultures of HTLV-III--infected T cells: a model of cytopathology of T-cell depletion in AIDS.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

1 reference

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7 January 2021

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

ATM and ATR: sensing DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Lentiviral delivery of HIV-1 Vpr protein induces apoptosis in transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

DNA damage-inducible transcripts in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Mechanisms of apoptosis induction by nucleoside analogs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

1 reference

7 January 2021

Poly(ADP-ribose) polymerase cleavage during apoptosis: when and where?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Analysis of apoptosis induced by HIV-1 Vpr and examination of the possible role of the hHR23A protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

The role of Vpr in HIV-1 pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Studies with GFP-Vpr fusion proteins: induction of apoptosis but ablation of cell-cycle arrest despite nuclear membrane or nuclear localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Induction of apoptosis by the Vpr protein of human immunodeficiency virus type 1 occurs independently of G(2) arrest of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Impact on genetic networks in human macrophages by a CCR5 strain of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401565

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401565

1 reference

Dimensions Publication ID

29 November 2017

0 references

1 reference