(Q35603389)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Mechanisms of apoptosis induction by nucleoside analogs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

V Ashutosh Rao

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

William Plunkett

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

1 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

9063-9074

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14663485%20AND%20SRC:MED&resulttype=core&format=json

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Dynamics of the dATP pool in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Biochemical pathways of caspase activation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Extended follow-up of patients with hairy cell leukemia after treatment with cladribine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Multiple signaling pathways involving ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

5-Fluorouracil: mechanisms of action and clinical strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Shared pathways: death receptors and cytotoxic drugs in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Fluorouracil: biochemistry and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Phosphorylation of Human Rad9 Is Required for Genotoxin-activated Checkpoint Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Activation of an ataxia telangiectasia mutation-dependent intra-S-phase checkpoint by anti-tumour drugs in HL-60 and human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Chk1 signaling pathways that mediated G(2)M checkpoint in relation to the cellular resistance to the novel topoisomerase I poison BNP1350.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Gemcitabine treatment in pretreated cutaneous T-cell lymphoma: experience in 44 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Deoxyguanosine toxicity on lymphoid cells as a cause for immunosuppression in purine nucleoside phosphorylase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Deoxyguanosine Triphosphate as a Possible Toxic Metabolite in the Immunodeficiency Associated with Purine Nucleoside Phosphorylase Deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The importance of repairing stalled replication forks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The purine path to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The combination of fludarabine and cyclophosphamide results in a high remission rate with moderate toxicity in low-grade non-Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The fundamental role of epigenetic events in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Regulation of p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Mechanisms for T-cell selective cytotoxicity of arabinosylguanine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Gemcitabine in the treatment of refractory Hodgkin's disease: results of a multicenter phase II study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Solution structure of a DNA dodecamer containing the anti-neoplastic agent arabinosylcytosine: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The inhibition of ultraviolet radiation-induced DNA repair in human diploid fibroblasts by arabinofuranosyl nucleosides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207229

7 January 2021