(Q34310555)

1 August 2017

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title

Shared pathways: death receptors and cytotoxic drugs in cancer therapy (English)

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1 August 2017

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Peták I

1

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PubMed ID

11458271

1 August 2017

Houghton JA

series ordinal

2

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1 August 2017

1 January 2001

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Pathology Oncology Research

1 August 2017

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1 August 2017

7

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1 August 2017

95-106

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1 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/bf03032574

1 August 2017

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cites work

Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03032574

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03032574

The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03032574

Signal transduction of stress via ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03032574

The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03032574

p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines

21 January 2018

1 reference

12 December 2020

Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

1 reference

12 December 2020

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

1 reference

12 December 2020

Requirement of FADD for tumor necrosis factor-induced activation of acid sphingomyelinase

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12 December 2020

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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12 December 2020

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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12 December 2020

Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells

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12 December 2020

Signal transduction through lipid second messengers

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12 December 2020

Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells

1 reference

12 December 2020

The chemotherapeutic drug 5-fluorouracil induces apoptosis in mouse thymocytes in vivo via activation of the CD95(APO-1/Fas) system.

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12 December 2020

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12 December 2020

The receptor for the cytotoxic ligand TRAIL

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12 December 2020

Inhibition of death receptor signals by cellular FLIP

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12 December 2020

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

12 December 2020

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

12 December 2020

Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism

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12 December 2020

Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells

1 reference

12 December 2020

TRAIL: a molecule with multiple receptors and control mechanisms

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12 December 2020

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

12 December 2020

The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

1 reference

12 December 2020

Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA.

1 reference

12 December 2020

A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs

1 reference

12 December 2020

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

12 December 2020

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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12 December 2020

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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12 December 2020

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

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12 December 2020

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

12 December 2020

Differential involvement of the CD95 (Fas/APO-1) receptor/ligand system on apoptosis induced by the wild-type p53 gene transfer in human cancer cells

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12 December 2020

JNK/SAPK activity is not sufficient for anticancer therapy-induced apoptosis involving CD95-L, TRAIL and TNF-alpha

1 reference

12 December 2020

Chemotherapy augments TRAIL-induced apoptosis in breast cell lines

1 reference

12 December 2020

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line.

1 reference

12 December 2020

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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12 December 2020

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

1 reference

12 December 2020

A novel adenoviral vector expressing human Fas/CD95/APO-1 enhances p53-mediated apoptosis

1 reference

12 December 2020

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

12 December 2020

An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells

1 reference

12 December 2020

Apoptosis provides new targets for chemotherapy

1 reference

12 December 2020

Thymineless death in colon carcinoma cells is mediated via fas signaling

1 reference

12 December 2020

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

1 reference

12 December 2020

Etoposide at different concentrations may open different apoptotic pathways in thymocytes.

1 reference

12 December 2020

Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.

1 reference

12 December 2020

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

12 December 2020

Gene transfer of Fas ligand induces tumor regression in vivo

1 reference

12 December 2020

Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells

1 reference

12 December 2020

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

12 December 2020

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

12 December 2020

Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

1 reference

12 December 2020

Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells

1 reference

12 December 2020

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

1 reference

12 December 2020

BCNU is a caspase-mediated inhibitor of drug-induced apoptosis

1 reference

12 December 2020

Mechanisms of ceramide-mediated apoptosis

1 reference

12 December 2020

Two CD95 (APO-1/Fas) signaling pathways

1 reference

12 December 2020

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

12 December 2020

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

12 December 2020

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

12 December 2020

Bleomycin, an apoptosis-mimetic drug that induces two types of cell death depending on the number of molecules internalized

1 reference

12 December 2020

Activation of the transcription factor kappa B in human KG-1 myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine

1 reference

12 December 2020

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Enhancement of Fas-mediated apoptosis in renal cell carcinoma cells by adriamycin.

1 reference

12 December 2020

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

1 reference

12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

12 December 2020

Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B story

1 reference

12 December 2020

Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases).

1 reference

12 December 2020

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

1 reference

12 December 2020

Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.

1 reference

12 December 2020

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

1 reference

12 December 2020

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

12 December 2020

Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.

1 reference

12 December 2020

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

12 December 2020

TRAIL/Apo-2-ligand-induced apoptosis in human T cells.

1 reference

12 December 2020

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

12 December 2020

A trial to kill tumor cells through Fas (CD95)-mediated apoptosis in vivo

1 reference

12 December 2020

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

12 December 2020

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

12 December 2020

Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells.

1 reference

12 December 2020

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

1 reference

12 December 2020

Apoptosis control by death and decoy receptors

1 reference

12 December 2020

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

12 December 2020

Metalloproteinase-mediated release of human Fas ligand

1 reference

12 December 2020

1 reference

12 December 2020

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover

1 reference

12 December 2020

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

12 December 2020

Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

1 reference

12 December 2020

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

12 December 2020

A novel receptor for Apo2L/TRAIL contains a truncated death domain

1 reference

12 December 2020

Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression.

1 reference

12 December 2020

Apoptosis mediated by the TNF-related cytokine and receptor families

1 reference

12 December 2020

A Fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells

1 reference

12 December 2020

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

12 December 2020

Regulation of FasL by NF-κB and AP-1 in Fas-dependent Thymineless Death of Human Colon Carcinoma Cells

1 reference

12 December 2020

Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

1 reference

12 December 2020

Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.

1 reference

12 December 2020

The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression.

1 reference

12 December 2020

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

1 reference

12 December 2020

Fatty acyl-Co A: sphingosine acyltransferase in bovine brain mitochondria: its solubilization and reconstitution onto the membrane lipid liposomes

1 reference

12 December 2020

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

12 December 2020

TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase

1 reference

12 December 2020

Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells

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12 December 2020

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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12 December 2020

Fas-dependent and -independent mechanisms of cell death following DNA damage in human colon carcinoma cells.

1 reference

12 December 2020

Identification and characterization of a new member of the TNF family that induces apoptosis

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12 December 2020

Apoptosis and cancer drug targeting

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12 December 2020

Cisplatin induces a persistent activation of JNK that is related to cell death

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12 December 2020

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

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12 December 2020

Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium

1 reference

12 December 2020

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

12 December 2020

Sphingomyelin breakdown and cell fate

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12 December 2020

Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.

1 reference

12 December 2020

c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

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12 December 2020

The stress-activated protein kinase subfamily of c-Jun kinases

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12 December 2020

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

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12 December 2020

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

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12 December 2020

p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells

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12 December 2020

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

1 reference

12 December 2020

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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12 December 2020

Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor

1 reference

12 December 2020

Fas ligand mediates activation-induced cell death in human T lymphocytes

1 reference

12 December 2020

Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions

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12 December 2020

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

12 December 2020

Etoposide-induced apoptosis is not associated with the fas pathway in acute myeloblastic leukemia cells

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12 December 2020

Functions of ceramide in coordinating cellular responses to stress

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12 December 2020

Regulation of CD95 expression and CD95-mediated cell death by interferon-gamma in acute lymphoblastic leukemia with chromosomal translocation t(4;11).

1 reference

12 December 2020

FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

1 reference

12 December 2020

p53-dependent ceramide response to genotoxic stress

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12 December 2020

Expression of TRAIL and its receptors in human brain tumors

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12 December 2020

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

12 December 2020

TRAIL death pathway expression and induction in thyroid follicular cells

1 reference

12 December 2020

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1 reference

12 December 2020

Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells

1 reference

12 December 2020

APO2 ligand: a novel lethal weapon against malignant glioma?

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12 December 2020

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

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12 December 2020

Apoptosis induced by anticancer drugs

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12 December 2020

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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12 December 2020

Downregulation of Fas ligand by shedding

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12 December 2020

The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells

1 reference

12 December 2020

Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation

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12 December 2020

Identifiers

DOI

10.1007/BF03032574

1 reference

1 August 2017

1 reference

PubMed ID

11458271