(Q27640324)

5

object named as

Matthew R Redinbo

0 references

Alex B. Burgin

2

object named as

Alex B Burgin

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author name string

Jill E Chrencik

1

0 references

Lance Stewart

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

4 April 2003

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published in

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volume

278

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issue

14

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page(s)

12461-6

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cites work

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A model for the mechanism of human topoisomerase I

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DNA topoisomerases as anticancer drug targets: from the laboratory to the clinic

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Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

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Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

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Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine

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Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

21 January 2018

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Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells

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8-Oxoguanine rearranges the active site of human topoisomerase I

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Acute myelogenous leukemia: current treatment and future directions.

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DNA damage in ultraviolet-irradiated HeLa and CHO-Kl cells examined by alkaline lysis and hydroxyapatite chromatography

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Solution structure of a DNA dodecamer containing the anti-neoplastic agent arabinosylcytosine: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement

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Molecular structure of a DNA decamber containing an anticancer nucleoside arabinosylcytosine: conformational perturbation by arabinosylcytosine in B-DNA.

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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

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Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures

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Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA

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A novel suicide substrate for DNA topoisomerases and site-specific recombinases

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Melanoplus sanguinipes entomopoxvirus DNA topoisomerase: site-specific DNA transesterification and effects of 5'-bridging phosphorothiolates.

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Suicide substrates reveal properties of the homology-dependent steps during integrative recombination of bacteriophage lambda.

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DNA contacts by protein domains of the molluscum contagiosum virus type-1B topoisomerase

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Catalytic mechanism of DNA topoisomerase IB.

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Regulation of site-specific recombination by the C-terminus of lambda integrase

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Reconstitution of human topoisomerase I by fragment complementation

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Processing of X-ray diffraction data collected in oscillation mode

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Assessment of phase accuracy by cross validation: the free R value. Methods and applications

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PROCHECK: a program to check the stereochemical quality of protein structures

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Raster3D: photorealistic molecular graphics

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Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.

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Modulation of ara-C induced apoptosis in leukemia by the PKC activator bryostatin 1.

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Simple statistics for intensity data from twinned specimens

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