(Q44082409)

29 November 2017

title

Inhibition of mitochondrial permeability transition and release of cytochrome c by anti-apoptotic nucleoside analogues (English)

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29 November 2017

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Luzheng Xue

1

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29 November 2017

Vilma Borutaite

series ordinal

2

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29 November 2017

Aviva M Tolkovsky

series ordinal

3

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29 November 2017

language of work or name

English

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publication date

1 August 2002

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29 November 2017

published in

Biochemical Pharmacology

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29 November 2017

volume

64

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29 November 2017

issue

3

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29 November 2017

page(s)

441-449

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Mitochondrion as a novel target of anticancer chemotherapy

29 November 2017

cites work

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Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

7 January 2021

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Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside

7 January 2021

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A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside.

7 January 2021

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Cytarabine and neurologic toxicity

7 January 2021

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Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury

7 January 2021

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Cyclosporin A protects against ischemia-reperfusion injury in the brain

7 January 2021

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Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

7 January 2021

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Case report: cyclosporin A-induced neurotoxicity

7 January 2021

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Clinical findings and magnetic resonance imaging in severe cyclosporine-related neurotoxicity after allogeneic bone marrow transplantation

7 January 2021

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Cyclosporine neurotoxicity

7 January 2021

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Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain

7 January 2021

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Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

7 January 2021

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Cyclosporin A inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin

7 January 2021

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

7 January 2021

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3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism

7 January 2021

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Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution

7 January 2021

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Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.

7 January 2021

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

7 January 2021

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7 January 2021

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Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors

7 January 2021

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Survival-promoting activity of inhibitors of cyclin-dependent kinases on primary neurons correlates with inhibition of c-Jun kinase-1

7 January 2021

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Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

7 January 2021

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Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death

7 January 2021

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Release of cytochrome c from heart mitochondria is induced by high Ca2+ and peroxynitrite and is responsible for Ca(2+)-induced inhibition of substrate oxidation.

7 January 2021

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Some observations on the photometric estimation of mitochondrial volume

7 January 2021

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Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction

7 January 2021

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Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator

7 January 2021

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Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

7 January 2021

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Mitochondrial intermembrane junctional complexes and their role in cell death

7 January 2021

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Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

7 January 2021

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Metabolism, mitochondrial uptake and toxicity of 2', 3'-dideoxycytidine.

7 January 2021

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Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs

7 January 2021

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Characterization of a dCTP transport activity reconstituted from human mitochondria

7 January 2021

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Involvement of oxygen radicals in cytarabine-induced apoptosis in human polymorphonuclear cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901181-4

Transport of calcium by mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901181-4

Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane

7 January 2021

1 reference

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Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901181-4

10.1016/S0006-2952(02)01181-4

7 January 2021

Identifiers

DOI

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29 November 2017

1 reference