(Q44082654)

English

beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats

scientific article published on 29 July 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

phenylacetic acid

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

author name string

Ye Qi Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Thomas L Jetton

2

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Jack L Leahy

3

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

language of work or name

0 references

publication date

29 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

277

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

39163-39168

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Role of insulin resistance in human disease (syndrome X): an expanded definition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Improved glycemic control and lipid profile and normalized fibrinolytic activity on a low-glycemic index diet in type 2 diabetic patients.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Glucose-stimulated insulin secretion does not require activation of pyruvate dehydrogenase: impact of adenovirus-mediated overexpression of PDH kinase and PDH phosphate phosphatase in pancreatic islets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Glucose-fatty acid cycle to inhibit glucose utilization and oxidation is not operative in fatty acid-cultured islets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for a plasma membrane aldehyde reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Leptin receptor missense mutation in the fatty Zucker rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

A simple, rapid, and sensitive DNA assay procedure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Glucagon secretion from the perfused rat pancreas. Studies with glucose and catecholamines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Shared biochemical properties of glucotoxicity and lipotoxicity in islets decrease citrate synthase activity and increase phosphofructokinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Fatty acid-induced beta cell hypersensitivity to glucose. Increased phosphofructokinase activity and lowered glucose-6-phosphate content

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

New insights into pancreatic beta-cell metabolic signaling in insulin secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Critical role for cataplerosis via citrate in glucose-regulated insulin release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Overexpression of mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase does not correct glucose-stimulated insulin secretion from diabetic GK rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207157200

21 January 2018

Identifiers

10.1074/JBC.M207157200

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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